⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954953 | 1.00 | — | — | |
| SCHEMBL10172376 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL11129917 | 0.98 | — | — | |
| SCHEMBL13227961 | 0.82 | — | — | |
| SCHEMBL2614011 | 0.82 | — | — | |
| SCHEMBL13233684 | 0.82 | — | — | |
| SCHEMBL8976122 | 0.81 | — | — | |
| SCHEMBL10786570 | 0.81 | — | — | |
| Urea SCHEMBL22721245 | 0.81 | KDM4E (0.54) | — | |
| Acetamide SCHEMBL27901069 | 0.79 | ALOX15 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166114-B | Cyclic tetramer compounds as inhibitors of proprotein convertase subtilisin/KEXIN type 9 (PCSK 9) for the treatment of metabolic disorders | 诺华股份有限公司 | 2025-01-03 | — | — | CN | disclosed |
| WO-2022271536-A1 | SYNTHESIS OF COVALENT PROTEIN DIMERS THAT CAN INHIBIT MYC-DRIVEN TRANSCRIPTION | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2022-12-29 | — | — | WO | disclosed |
| US-20200407409-A1 | EGF(A) ANALOGUES WITH FATTY ACID SUBSTITUENTS | CHEN JIANHE (CN) | 2020-12-31 | — | — | US | disclosed |
| US-20200165313-A1 | EGF(A) ANALOGUES, PREPARATION, FORMULATIONS AND USES THEREOF | NOVO NORDISK A/S (DK) | 2020-05-28 | — | — | US | disclosed |
| EP-2768971-A1 | METHODS FOR THE DETECTION AND THE TREATMENT OF CARDIAC REMODELING | Institut National de la Santé et de la Recherche Médicale (INSERM) (FR) | 2014-08-27 | — | — | EP | disclosed |
| WO-2013057313-A1 | METHODS FOR THE DETECTION AND THE TREATMENT OF CARDIAC REMODELING | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2013-04-25 | — | — | WO | disclosed |
| WO-2009156462-A2 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2009-12-30 | — | — | WO | disclosed |
| EP-0488144-A1 | Benzodioxole derivatives and hepatopathy improvers comprising the same | TSUMURA & CO. (JP) | 1992-06-03 | — | — | EP | disclosed |
| EP-0051682-B1 | CYSTEINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | MITSUBISHI KASEI CORPORATION (JP) | 1984-09-05 | — | — | EP | disclosed |
| US-4440788-A | REGENERATION OF LIVER CELLS | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1984-04-03 | — | — | US | disclosed |
| EP-0051682-A1 | CYSTEINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | MITSUBISHI KASEI CORPORATION (JP) | 1982-05-19 | — | — | EP | disclosed |