Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.58 |
| ▸ | MST1R | Q04912 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2450541 | 0.84 | MET (0.55) | METMST1RKCNH2 | |
| SCHEMBL2322770 | 0.79 | MET (0.72) | METMST1RKCNH2 | |
| SCHEMBL2447227 | 0.78 | MET (0.77) | METMST1RKCNH2 | |
| SCHEMBL2448744 | 0.77 | MET (0.72) | METMST1RKCNH2 | |
| SCHEMBL4320835 | 0.75 | MET (0.61) | METMST1RKCNH2 | |
| SCHEMBL2329079 | 0.74 | MET (1.00) | METKCNH2 | |
| SCHEMBL399405 | 0.74 | MET (0.65) | METMST1R | |
| SCHEMBL397631 | 0.73 | MET (0.52) | METMST1RKCNH2 | |
| SCHEMBL2446446 | 0.71 | MET (0.70) | METMST1RKCNH2 | |
| SCHEMBL2330091 | 0.71 | MET (0.59) | METKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090197908-A1 | Benzocycloheptapyridines as inhibitors of the receptor tyrosine kinase met | MERCK SHARP & DOHME LLC | 2009-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090197908-A1 | Benzocycloheptapyridines as inhibitors of the receptor tyrosine kinase met | MET, RET, ERBB2 | MET 1/4885MST1R 62/4885KCNH2 3862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.