Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 3/20 | 0.43 |
| ▸ | NPY4R | P50391 | 13/20 | 0.40 |
| ▸ | NPY1R | P25929 | 8/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.40 |
| ▸ | NPY2R | P49146 | 4/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7402070 | 0.86 | PTGER4 (0.44) | PTGER4NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL7402074 | 0.86 | PTGER4 (0.44) | PTGER4NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL9022219 | 0.85 | PTGER4 (0.46) | PTGER4NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL14655995 | 0.83 | PTGER4 (0.42) | PTGER4NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL1575643 | 0.83 | NPY4R (0.43) | PTGER4NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL12493203 | 0.82 | MAOB (0.46) | MAOAMAOBMMP2MMP9ADAM17 | |
| SCHEMBL4796989 | 0.82 | MAOB (0.46) | MAOAMAOBMMP2MMP9ADAM17 | |
| SCHEMBL7358758 | 0.79 | PTGER4 (0.58) | PTGER4MAOB | |
| SCHEMBL4413420 | 0.79 | PTGER4 (0.58) | PTGER4MAOB | |
| SCHEMBL5614017 | 0.79 | MAOB (0.41) | BACE1MAOAMAOBMMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160168235-A1 | TRANSTHYRETIN AMYLOID-SELECTIVE AND POLYREACTIVE CATABODIES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-06-16 | — | — | US | claimed |
| EP-3022225-A2 | TRANSTHYRETIN AMYLOID-SELECTIVE AND POLYREACTIVE CATABODIES | Board Of Regents Of the University Of Texas System (US) | 2016-05-25 | — | — | EP | claimed |
| WO-2015010118-A2 | TRANSTHYRETIN AMYLOID-SELECTIVE AND POLYREACTIVE CATABODIES | THE UNIVERSITY OF TEXAS (US) | 2015-01-22 | — | — | WO | claimed |
| EP-3022225-B1 | TRANSTHYRETIN AMYLOID-SELECTIVE AND POLYREACTIVE CATABODIES | UNIV TEXAS (US) | 2021-09-29 | — | — | EP | disclosed |
| US-20160168235-A1 | TRANSTHYRETIN AMYLOID-SELECTIVE AND POLYREACTIVE CATABODIES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-06-16 | — | — | US | disclosed |
| US-20090297534-A1 | Catalytic Immunoglobulins BBK32 and Uses Therefor | PAUL SUDHIR | 2009-12-03 | — | — | US | disclosed |
| EP-1907423-A2 | CATALYTIC IMMUNOGLOBULINS | Coimmune Inc. (US) | 2008-04-09 | — | — | EP | disclosed |
| WO-2007011639-A2 | CATALYTIC IMMUNOGLOBULINS | COIMMUNE INC. (US) | 2007-01-25 | — | — | WO | disclosed |