Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RARA | P10276 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 5/20 | 0.45 |
| ▸ | THRB | P10828 | 5/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 4/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4295476 | 0.93 | SPHK1 (0.44) | ALDH1A1S1PR1S1PR3S1PR4S1PR5 | |
| Hydrochloric Acid SCHEMBL4290826 | 0.92 | SPHK1 (0.43) | ALDH1A1S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL4286874 | 0.91 | S1PR1 (0.41) | ALDH1A1S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL4296065 | 0.87 | SPHK1 (0.40) | ALDH1A1S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL4296545 | 0.87 | SPHK1 (0.40) | ALDH1A1S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL4288723 | 0.86 | THRA (0.42) | ALDH1A1S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL4289401 | 0.82 | SPHK1 (0.42) | S1PR1S1PR3S1PR4S1PR5THRA | |
| SCHEMBL4295706 | 0.81 | THRA (0.47) | ALDH1A1S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL4293674 | 0.80 | TSHR (0.36) | S1PR1MEN1MAPTKMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL4632549 | 0.80 | SPHK1 (0.42) | ALDH1A1S1PR1S1PR3S1PR4S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090264469-A1 | NOVEL DICARBOXYLIC ACID DERIVATIVES | BIO-PROJET (FR) | 2009-10-22 | — | — | US | claimed |
| WO-2006043149-A2 | NOVEL DICARBOXYLIC ACID DERIVATIVES | BIOPROJET (FR) | 2006-04-27 | — | — | WO | claimed |
| US-20090264469-A1 | NOVEL DICARBOXYLIC ACID DERIVATIVES | BIO-PROJET (FR) | 2009-10-22 | — | — | US | disclosed |
| WO-2006043149-A9 | NOVEL DICARBOXYLIC ACID DERIVATIVES | BIOPROJET SOC CIV (FR) | 2006-08-10 | — | — | WO | disclosed |
| WO-2006043149-A2 | NOVEL DICARBOXYLIC ACID DERIVATIVES | BIOPROJET (FR) | 2006-04-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264469-A1 | NOVEL DICARBOXYLIC ACID DERIVATIVES | S1PR2, S1PR1, S1PR5 | ALDH1A1 1287/4885S1PR1 2/4885S1PR3 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.