Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 5/20 | 0.41 |
| ▸ | MAOA | P21397 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 10/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 10/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 9/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7135197 | 0.98 | NISCH (0.41) | NISCHMAOAMAOBADRA2BADRA2C | |
| SCHEMBL1992259 | 0.84 | ADRA2B (0.36) | NISCHMAOAMAOBADRA2BADRA2C | |
| SCHEMBL4912194 | 0.82 | ADRA2B (0.43) | NISCHMAOAMAOBADRA2BADRA2C | |
| SCHEMBL3264669 | 0.77 | — | — | |
| SCHEMBL9754198 | 0.77 | ADRA2B (0.38) | NISCHMAOAMAOBADRA2BADRA2C | |
| SCHEMBL1326510 | 0.76 | ADRA2B (0.38) | NISCHMAOAMAOBADRA2BADRA2C | |
| SCHEMBL25143431 | 0.74 | — | — | |
| SCHEMBL947803 | 0.74 | — | — | |
| SCHEMBL9439738 | 0.70 | — | — | |
| SCHEMBL1768228 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1357067-A | Antistats for high temp short heater texturing | ORGNESS CORP (US) | 2002-07-03 | — | — | CN | claimed |
| US-5342961-A | Process for the production of low-viscosity imidazolinium surfactants by quaternization of 1-hydroxyethyl-2-alkyl imidazolines | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1994-08-30 | — | — | US | claimed |
| US-4567132-A | Multi-level resist image reversal lithography process | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1986-01-28 | — | — | US | claimed |
| JP-3186305-A | — | — | None | — | — | JP | disclosed |
| US-20230286924-A1 | CRYSTALLINE FORMS OF 4-(7-HYDROXY-2-ISOPROPYL-4-OXO-4H-QUINAZOLIN-3-YL)-BENZONITRILE AND FORMULATIONS THEREOF | CITIBANK, N.A., AS NOTES COLLATERAL AGENT | 2023-09-14 | — | — | US | disclosed |
| CN-111568906-B | Formulations of 4- (7-hydroxy-2-isopropyl-4-oxo-4H-quinazolin-3-yl) -benzonitrile | 诺华股份有限公司 | 2023-09-01 | — | — | CN | disclosed |
| CN-116648670-A | Method for manufacturing light-emitting device and light-emitting device | 夏普株式会社 | 2023-08-25 | — | — | CN | disclosed |
| CN-116419918-A | Crystalline forms of 4- (7-hydroxy-2-isopropyl-4-oxo-4H-quinazolin-3-yl) -benzonitrile and formulations thereof | 诺华股份有限公司 | 2023-07-11 | — | — | CN | disclosed |
| EP-4192466-A1 | CRYSTALLINE FORMS OF 4-(7-HYDROXY-2-ISOPROPYL-4-OXO-4H-QUINAZOLIN-3-YL)-BENZONITRILE AND FORMULATIONS THEREOF | Novartis AG (CH) | 2023-06-14 | — | — | EP | disclosed |
| US-20230139170-A1 | Formulations of 4-(7-Hydroxy-2-isopropyl-4-oxo-4H-quinazolin-3-yl)-benzonitrile | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR AGENT | 2023-05-04 | — | — | US | disclosed |
| US-11584829-B2 | Methods for preparing waterborne heat seal coating compositions | DOW GLOBAL TECHNOLOGIES LLC (US) | 2023-02-21 | — | — | US | disclosed |
| EP-0216955-A1 | Method for preparing an electrolyte solution for electroplating tin or tin-lead alloys | LeaRonal, Inc. (US) | 1987-04-08 | — | — | EP | disclosed |
| US-4617097-A | Process and electrolyte for electroplating tin, lead or tin-lead alloys | LEARONAL, INC. (US) | 1986-10-14 | — | — | US | disclosed |
| US-4567132-A | Multi-level resist image reversal lithography process | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1986-01-28 | — | — | US | disclosed |
| EP-0164248-A2 | Photosensitive coating compositions, thermally stable coatings prepared from them, and the use of such coatings in forming thermally stable polymer images | ROHM AND HAAS COMPANY (US) | 1985-12-11 | — | — | EP | disclosed |
| US-4503002-A | CATIONIC SURFACTANTS | MONA INDUSTRIES, INC. (US) | 1985-03-05 | — | — | US | disclosed |
| US-4293097-A | Method for brightening natural calcitic ores | ANGLO-AMERICAN CLAYS CORPORATION (US) | 1981-10-06 | — | — | US | disclosed |
| US-4124632-A | AMPHOTERIC COMPOUNDS WITH TWO BASIC GROUPS, ONE OF WHICH IS QUATERNARY AMMONIUM, AND A CARBOXYLIC ANIONIC GROUP | SOCIETE ANONYME DITE L'OREAL (FR) | 1978-11-07 | — | — | US | disclosed |
| US-4104070-A | Method of making a negative photoresist image | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1978-08-01 | — | — | US | disclosed |
| US-4020155-A | AMPHOTERIC COSMETIC | SOCIETE ANONYME DITE: L'OREAL (FR) | 1977-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230139170-A1 | Formulations of 4-(7-Hydroxy-2-isopropyl-4-oxo-4H-quinazolin-3-yl)-benzonitrile | HRH4, AQP4, P2RY4 | NISCH 143/4885MAOA 2071/4885MAOB 2076/4885 |
| US-20230286924-A1 | CRYSTALLINE FORMS OF 4-(7-HYDROXY-2-ISOPROPYL-4-OXO-4H-QUINAZOLIN-3-YL)-BENZONITRILE AND FORMULATIONS THEREOF | P2RY4, AQP4, P2RX4 | NISCH 238/4885MAOA 1857/4885MAOB 1918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.