Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5143813 | 0.83 | MGAM (0.44) | ALDH1A1KMT2ALMNAHSD17B10TSHR | |
| SCHEMBL9782172 | 0.81 | ALDH1A1 (0.39) | ALDH1A1SLC22A6MEN1NPC1KMT2A | |
| SCHEMBL10714698 | 0.81 | ABCB1 (0.39) | SLC22A6KMT2ALMNASMN1; SMN2 | |
| SCHEMBL5082871 | 0.80 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10TSHRALOX15 | |
| SCHEMBL5082863 | 0.80 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10TSHRALOX15 | |
| SCHEMBL1548356 | 0.78 | MEN1 (0.36) | ALDH1A1SLC22A6MEN1NPC1KMT2A | |
| SCHEMBL5146404 | 0.77 | CACNA2D1 (0.39) | ALDH1A1SLC22A6MEN1NPC1KMT2A | |
| SCHEMBL14886388 | 0.77 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10TSHRALOX15 | |
| SCHEMBL5576933 | 0.77 | MGAM (0.46) | ALDH1A1SLC22A6LMNAHSD17B10TSHR | |
| SCHEMBL19318891 | 0.77 | ALDH1A1 (0.53) | ALDH1A1MEN1NPC1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009038412-A2 | BETA-SECRETASE INHIBITING COMPOUNDS | LG LIFE SCIENCES, LTD. (KR) | 2009-03-26 | — | — | WO | disclosed |