SCHEMBL4299053

SCHEMBL4299053

COc1c(-c2ccccc2)oc2c(O)c(O)c(O)c(O)c2c1=O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.65
MAPT P10636 4/20 0.65
GAA P10253 3/20 0.65
ALDH1A1 P00352 3/20 0.65
ABCB1 P08183 2/20 0.59
ADORA3 P0DMS8 1/20 0.55
ABCG2 Q9UNQ0 3/20 0.55
ABCC1 P33527 1/20 0.54
KIT P10721 1/20 0.53
CYP1A1 P04798 3/20 0.53
CYP1B1 Q16678 3/20 0.53
CYP1A2 P05177 2/20 0.53
BCL9 O00512 1/20 0.53
CTNNB1 P35222 1/20 0.53
TUBB4A P04350 1/20 0.52
TUBB P07437 1/20 0.52
TUBA3C P0DPH7 1/20 0.52
TUBA1B P68363 1/20 0.52
TUBA4A P68366 1/20 0.52
TUBB4B P68371 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27881183 0.93 MAPT (0.67) KDM4EMAPTGAAALDH1A1ABCB1
SCHEMBL27972009 0.93 KDM4E (0.64) KDM4EMAPTGAAALDH1A1ABCB1
SCHEMBL27973635 0.93 KDM4E (0.60) KDM4EMAPTGAAALDH1A1ABCB1
SCHEMBL29712284 0.93 KDM4E (0.60) KDM4EMAPTGAAALDH1A1ABCB1
SCHEMBL27783737 0.91 MAPT (0.73) KDM4EMAPTGAAALDH1A1ABCB1
SCHEMBL28998302 0.87 MAPT (0.63) KDM4EMAPTGAAALDH1A1ABCB1
SCHEMBL31051345 0.87 KDM4E (0.67) KDM4EMAPTGAAALDH1A1ABCB1
SCHEMBL8049833 0.87 MAPT (0.71) KDM4EMAPTGAAALDH1A1ABCB1
SCHEMBL31558901 0.87 MAPT (0.85) KDM4EMAPTGAAALDH1A1ABCB1
SCHEMBL4129003 0.87 MAPT (0.85) KDM4EMAPTGAAALDH1A1ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108684901-B Macadamia nut peel tea and preparation method and application thereof 广西南亚热带农业科学研究所 2021-11-16 CN disclosed
CN-110483541-A A kind of isopentene group flavone compound and its preparation method and application UNIV HENAN CHINESE MEDICINE 2019-11-22 CN disclosed
CN-110483488-A A kind of isopentene group flavone compound and its preparation method and application UNIV HENAN CHINESE MEDICINE 2019-11-22 CN disclosed
CN-108684901-A A kind of Queensland nut pericarp tea and the preparation method and application thereof 广西南亚热带农业科学研究所 2018-10-23 CN disclosed
CN-105130940-B Preparation method and application of isopentenyl flavonoid compound with anti-breast cancer activity 河南中医学院 2017-04-05 CN disclosed
CN-105969632-A Processing method of vitex negundo leaf composite tea vinegar 章新华 2016-09-28 CN disclosed
CN-105943545-A Medicine composition and application thereof for treating memory disorder 中国航天员科研训练中心 2016-09-21 CN disclosed
CN-105168642-A Medical wine for treating scabies and preparing method of medical wine WANG XINGTONG 2015-12-23 CN disclosed
CN-105130940-A Preparation method and application of isopentenyl flavonoid compound with anti-breast cancer activity UNIV HENAN TCM 2015-12-09 CN disclosed
CN-104983953-A Ointment preparation for treating mange and preparation method thereof WANG XINGTONG 2015-10-21 CN disclosed
CN-103041045-B Chinese herbal medicine for treating acute lumbar sprain and lumbar muscle strain and preparation method of medicine JIANG ANNAN 2014-08-27 CN disclosed
WO-2013127017-A1 APIS MELLIFERA BEEKEEPING POLLEN EXTRACT AND METHOD FOR OBTAINING SAME, WHICH CAN BE USED IN THE FOOD INDUSTRY MONTENEGRO RIZZARDINI GLORIA (CL) 2013-09-06 WO disclosed
CN-103041045-A Chinese herbal medicine for treating acute lumbar sprain and lumbar muscle strain and preparation method of medicine JIANG ANNAN 2013-04-17 CN disclosed
CN-101152348-B Traditional Chinese medicine for treating diarrhea SHUNSHU YU 2012-04-18 CN disclosed
CN-102302618-A Summer-heat relieving agent QIN WANG 2012-01-04 CN disclosed
WO-2009125036-A1 NATURAL ANTIOXIDANT COMPOSITION FOR MEAT PRODUCTS PRODUCED FROM PHENOLIC EXTRACTS OF MONOFLORAL HONEYS, AND METHOD FOR OBTAINING SAME PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE (CL) 2009-10-15 WO disclosed
CN-101152348-A Traditional Chinese medicine for treating ringworm of the nails, dysentery and nephritis SHUNSHU YU (CN) 2008-04-02 CN disclosed