SCHEMBL4299825

SCHEMBL4299825

C#CC(CCC)OC(C)=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.36
CHRM1 P11229 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
AKR1A1 P14550 1/20 0.33
CHRM3 P20309 1/20 0.33
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
ADRA1A P35348 1/20 0.33
HRH1 P35367 1/20 0.33
DRD3 P35462 1/20 0.33
SLC6A3 Q01959 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
TBXA2R P21731 1/20 0.32
CYP3A4 P08684 2/20 0.32
NFKB1 P19838 2/20 0.32
NPSR1 Q6W5P4 2/20 0.32
GALR3 O60755 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11512142 0.88 FAAH (0.40) MAPTALDH1A1LMNAPRKCA
SCHEMBL11606407 0.88 FAAH (0.40) MAPTALDH1A1LMNAPRKCA
SCHEMBL11512138 0.88 FAAH (0.40) MAPTALDH1A1LMNAPRKCA
SCHEMBL4301873 0.85 CHRM1 (0.34) TSHRCHRM1TDP1AKR1A1CHRM3
SCHEMBL1535252 0.83 TSHR (0.36) TSHRCHRM1TDP1CHRM2CHRM4
SCHEMBL28216788 0.83 CHRM1 (0.38) TSHRCHRM1TDP1AKR1A1CHRM3
SCHEMBL22557813 0.83
SCHEMBL4300648 0.82 TSHR (0.39) TSHRCHRM1TDP1CHRM2CHRM4
SCHEMBL4298934 0.82 HDAC7 (0.33) TSHRCHRM1TDP1AKR1A1CHRM3
SCHEMBL6379373 0.81 TSHR (0.37) TSHRCHRM1TDP1AKR1A1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1772924-B1 NONAQUEOUS ELECTROLYTIC SOLUTION AND LITHIUM SECONDARY BATTERY UBE INDUSTRIES (JP) 2013-04-10 EP disclosed
US-7629085-B2 sulfur-containing acid ester and an alkyne-containing compound; excellent battery characteristics in cycle performance, electric capacity and storage property; e.g. 2-propynyl methyl carbonate and 1,3-propanesultone UBE INDUSTRIES, LTD. (JP) 2009-12-08 US disclosed
US-20070231707-A1 Nonaqueous Electrolytic Solution and Lithium Secondary Battery MU IONIC SOLUTIONS CORPORATION (JP) 2007-10-04 US disclosed
EP-1772924-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND LITHIUM SECONDARY BATTERY Ube Industries, Ltd. (JP) 2007-04-11 EP disclosed