Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.41 |
| ▸ | FAP | Q12884 | 1/20 | 0.41 |
| ▸ | CTSC | P53634 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 4/20 | 0.31 |
| ▸ | METAP1 | P53582 | 4/20 | 0.31 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4299887 | 0.83 | DPP4 (0.40) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL1627439 | 0.80 | DPP4 (0.42) | DPP4DPP8DPP7 | |
| SCHEMBL8509053 | 0.80 | DPP4 (0.42) | DPP4DPP8DPP7 | |
| SCHEMBL7139196 | 0.78 | DPP4 (0.47) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL11347414 | 0.78 | DPP4 (0.47) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL11347411 | 0.78 | DPP4 (0.47) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL4638730 | 0.77 | DPP4 (0.46) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL2182182 | 0.77 | DPP4 (0.46) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL27601749 | 0.77 | DPP4 (0.46) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL27179974 | 0.77 | DPP4 (0.46) | DPP4DPP8DPP9DPP7FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090263830-A1 | VISUALIZATION AND QUANTITIATION OF CELLULAR CYTOTOXICITY USING CELL-PERMEABLE FLUOROGENIC PROTEASE SUBSTRATES AND CASPASE ACTIVITY INDICATOR MARKERS | ONCOIMMUNIN, INC. (US) | 2009-10-22 | — | — | US | disclosed |