Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | CTRB1 | P17538 | 5/20 | 0.34 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8509053 | 1.00 | DPP4 (0.42) | DPP4PAX8DPP8DPP7CTRB1 | |
| SCHEMBL6466746 | 0.82 | PAX8 (0.45) | DPP4PAX8DPP8DPP7CTRB1 | |
| SCHEMBL1796260 | 0.81 | DPP4 (0.42) | DPP4PAX8DPP8DPP7CTRB1 | |
| SCHEMBL4299877 | 0.80 | DPP4 (0.41) | DPP4DPP8DPP7 | |
| SCHEMBL9797925 | 0.79 | DPP7 (0.47) | DPP4PAX8DPP8DPP7CTRB1 | |
| SCHEMBL1627442 | 0.79 | DPP4 (0.41) | DPP4PAX8DPP8DPP7CTRB1 | |
| SCHEMBL9797920 | 0.79 | DPP7 (0.47) | DPP4PAX8DPP8DPP7CTRB1 | |
| SCHEMBL9176465 | 0.77 | GABRP (0.47) | DPP4DPP8DPP7NOD1 | |
| SCHEMBL27585242 | 0.77 | GABRP (0.47) | DPP4DPP8DPP7NOD1 | |
| SCHEMBL9177741 | 0.77 | GABRP (0.47) | DPP4DPP8DPP7NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7927871-B2 | Visualization and quantitation of cellular cytotoxicity using cell-permeable fluorogenic protease substrates and caspase activity indicator markers | ONCOIMMUNIN, INC. (US) | 2011-04-19 | — | — | US | disclosed |
| US-20070184493-A1 | VISUALIZATION AND QUANTITATION OF CELLULAR CYTOTOXICITY USING CELL-PERMEABLE FLUOROGENIC PROTEASE SUBSTRATES AND CASPASE ACTIVITY INDICATOR MARKERS | ONCOIMMUNIN (US) | 2007-08-09 | — | — | US | disclosed |