Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.43 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6299977 | 0.80 | GAA (0.48) | TDP1L3MBTL1EPHX1GAAHTT | |
| SCHEMBL260323 | 0.79 | L3MBTL1 (0.55) | TDP1L3MBTL1EPHX1TP53HTT | |
| SCHEMBL5000353 | 0.79 | IDO1 (0.51) | TDP1L3MBTL1EPHX1TP53LMNA | |
| SCHEMBL157921 | 0.79 | IDO1 (0.50) | TDP1L3MBTL1EPHX1GAAIDO1 | |
| SCHEMBL29718886 | 0.79 | L3MBTL1 (0.55) | TDP1L3MBTL1EPHX1TP53HTT | |
| SCHEMBL29712851 | 0.79 | IDO1 (0.50) | TDP1L3MBTL1EPHX1GAAIDO1 | |
| SCHEMBL11256814 | 0.79 | KMT2A (0.47) | TDP1L3MBTL1GAAHTTIDO1 | |
| SCHEMBL6299218 | 0.77 | GAA (0.46) | TDP1L3MBTL1EPHX1GAAIDO1 | |
| SCHEMBL4300010 | 0.75 | KMT2A (0.47) | TDP1L3MBTL1EPHX1TP53LMNA | |
| SCHEMBL7641294 | 0.75 | GAA (0.50) | L3MBTL1GAALMNAHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009127722-A1 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-10-22 | — | — | WO | disclosed |