Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.73 |
| ▸ | HTT | P42858 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4300487 | 1.00 | SMN1; SMN2 (0.74) | SMN1; SMN2ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL6791019 | 0.85 | ALDH1A1 (0.80) | SMN1; SMN2ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL6791025 | 0.85 | ALDH1A1 (0.80) | SMN1; SMN2ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL8641053 | 0.82 | SMN1; SMN2 (0.72) | SMN1; SMN2ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL8641059 | 0.82 | SMN1; SMN2 (0.72) | SMN1; SMN2ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL17109793 | 0.81 | ALDH1A1 (0.88) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL6784387 | 0.80 | KMT2A (0.76) | SMN1; SMN2ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL6784388 | 0.80 | KMT2A (0.76) | SMN1; SMN2ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL11760920 | 0.78 | ALDH1A1 (0.62) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8065998 | 0.75 | TRPV1 (0.67) | SMN1; SMN2ALDH1A1HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009131384-A2 | PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING MALARIA, CONTAINING COMPOUNDS THAT INHIBIT PLASMEPSIN II ACTIVITY, AND METHOD OF TREATING MALARIA USING THE SAME | INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) | 2009-10-29 | — | — | WO | claimed |
| WO-2009131384-A2 | PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING MALARIA, CONTAINING COMPOUNDS THAT INHIBIT PLASMEPSIN II ACTIVITY, AND METHOD OF TREATING MALARIA USING THE SAME | INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) | 2009-10-29 | — | — | WO | disclosed |