Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 6/20 | 0.57 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1081739 | 0.84 | ADORA2A (0.57) | ADORA2AADORA2BADORA3KDM4EALOX15 | |
| Hydrochloric Acid SCHEMBL6754870 | 0.84 | ADORA2A (0.56) | ADORA2AADORA2BADORA3KDM4EALOX15 | |
| Hydrochloric Acid SCHEMBL2031973 | 0.83 | ADORA2A (0.55) | ADORA2AADORA2BADORA3KDM4EALOX15 | |
| SCHEMBL13516554 | 0.82 | ADORA2A (0.40) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL2295173 | 0.77 | ADORA2A (0.48) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL724838 | 0.76 | ADORA2A (0.47) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL726188 | 0.76 | ADORA2A (0.46) | ADORA2AADORA2BADORA3KDM4EALOX15 | |
| SCHEMBL846742 | 0.75 | HSPA8 (0.46) | ADORA2AADORA2BADORA3KDM4EALOX15 | |
| SCHEMBL940191 | 0.75 | ADORA2A (0.46) | ADORA2AADORA2BADORA3 | |
| SCHEMBL10588368 | 0.73 | ADORA2A (1.00) | ADORA2AADORA2BADORA3KDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7082156-A | — | — | None | — | — | JP | disclosed |
| US-20120197004-A1 | NOVEL ANTI-MICROBIAL PEPTIDOMIMETIC COMPOUNDS AND METHODS TO CALCULATE ANTI-MICROBIAL ACTIVITY | HICKS RICKEY P (US) | 2012-08-02 | — | — | US | disclosed |
| US-8188033-B2 | Anti-microbial peptidomimetic compounds and methods to calculate anti-microbial activity | USA AS REPRESENTED BY THE SECRETARY OF THE ARMY ON BEHALF OF USAMRMC | 2012-05-29 | — | — | US | disclosed |
| US-20090291898-A1 | Novel anti-microbial peptidomimetic compounds and methods to calculate anti-microbial activity | USA AS REPRESENTED BY THE SECRETARY OF THE ARMY ON BEHALF OF USAMRMC | 2009-11-26 | — | — | US | disclosed |
| EP-2120983-A2 | NOVEL ANTI-MICROBIAL PEPTIDOMIMETIC COMPOUNDS AND METHODS TO CALCULATE ANTI-MICROBIAL ACTIVITY | The United States of America, as represented by The Secretary of the Army, on behalf of The Walter Reed Army Institute of Research (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008079314-A2 | NOVEL ANTI-MICROBIAL PEPTIDOMIMETIC COMPOUNDS AND METHODS TO CALCULATE ANTI-MICROBIAL ACTIVITY | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE ARMY, ON BEHALF OF WALTER REED ARMY INSTITUTE OF RESEARCH (US) | 2008-07-03 | — | — | WO | disclosed |
| JP-H0782156-A | CANCER METASTASIS INHIBITOR | NIPPON ZEON CO LTD | 1995-03-28 | — | — | JP | disclosed |