SCHEMBL4300880

SCHEMBL4300880

Nc1ncnc2c1ncn2[C@@H]1O[C@H](COS(=O)(=O)OP(=O)(O)O)[C@@H](O)[C@H]1O

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RY1 P47900 5/20 0.75
P2RY2 P41231 4/20 0.75
TAS1R3 Q7RTX0 2/20 0.75
TAS1R1 Q7RTX1 2/20 0.75
SRC P12931 2/20 0.75
SMN1; SMN2 Q16637 2/20 0.75
TRPM2 O94759 2/20 0.75
DNPH1 O43598 1/20 0.75
PRKAB2 O43741 1/20 0.75
LDHA P00338 1/20 0.75
ADRB2 P07550 1/20 0.75
FBP1 P09467 1/20 0.75
ADORA1 P30542 1/20 0.75
PRKAG1 P54619 1/20 0.75
PRKAA2 P54646 1/20 0.75
PDE4D Q08499 1/20 0.75
KCNH2 Q12809 1/20 0.75
PRKAA1 Q13131 1/20 0.75
PDE3A Q14432 1/20 0.75
P2RY11 Q96G91 1/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4297492 0.92 ADORA1 (0.67) P2RY1P2RY2TAS1R3TAS1R1SRC
SCHEMBL4407203 0.90 TAS1R3 (0.85) P2RY1P2RY2TAS1R3TAS1R1SRC
SCHEMBL30208039 0.87 CA1 (0.73) P2RY1P2RY2TAS1R3TAS1R1SRC
SCHEMBL14201601 0.87 CA1 (0.73) P2RY1P2RY2TAS1R3TAS1R1SRC
SCHEMBL2294870 0.87 CA1 (0.73) P2RY1P2RY2TAS1R3TAS1R1SRC
SCHEMBL2294876 0.87 CA1 (0.73) P2RY1P2RY2TAS1R3TAS1R1SRC
SCHEMBL28305441 0.87 P2RY1 (0.73) P2RY1P2RY2TAS1R3TAS1R1SRC
Adenosine Phosphate SCHEMBL30298370 0.87 P2RY1 (0.92) P2RY1P2RY2TAS1R3TAS1R1SRC
Adenosine Phosphate SCHEMBL1829884 0.87 P2RY1 (0.92) P2RY1P2RY2TAS1R3TAS1R1SRC
Adenosine Phosphate SCHEMBL1448053 0.87 P2RY1 (0.92) P2RY1P2RY2TAS1R3TAS1R1SRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090298136-A1 Methionine producing recombinant microorganisms BASF AG (DE) 2009-12-03 US disclosed
EP-1954827-A1 RAPID PARALLEL NUCLEIC ACID ANALYSIS GE Healthcare Bio-Sciences Corp. (US) 2008-08-13 EP disclosed
EP-1907559-A1 METHIONINE PRODUCING RECOMBINANT MICROORGANISMS BASF SE (DE) 2008-04-09 EP disclosed
WO-2007048033-A1 RAPID PARALLEL NUCLEIC ACID ANALYSIS GE HEALTHCARE BIO-SCIENCES CORP. (US) 2007-04-26 WO disclosed
US-7176354-B2 Genes encoding sulfate assimilation proteins E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-02-13 US disclosed
WO-2007012078-A1 METHIONINE PRODUCING RECOMBINANT MICROORGANISMS BASF AG (DE) 2007-01-25 WO disclosed
US-20040177401-A1 Genes encoding sulfate assimilation proteins E. I. DU PONT DE NEMOURS AND COMPANY 2004-09-09 US disclosed