Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.78 |
| ▸ | PPARA | Q07869 | 7/20 | 0.78 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KLK7 | P49862 | 3/20 | 0.43 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4301070 | 0.88 | PPARG (0.79) | PPARGPPARASLC6A4TSHRFFAR1 | |
| SCHEMBL978223 | 0.88 | PPARG (1.00) | PPARGPPARA | |
| SCHEMBL10688303 | 0.82 | FFAR1 (0.55) | PPARGPPARASLC6A4TSHRHAO1 | |
| SCHEMBL977816 | 0.78 | PPARG (1.00) | PPARGPPARA | |
| SCHEMBL27808291 | 0.76 | PPARG (0.53) | PPARGPPARATSHRKLK7ACE | |
| SCHEMBL978222 | 0.73 | PPARG (0.62) | PPARGPPARATSHRKLK7ACE | |
| SCHEMBL27002598 | 0.72 | NPY1R (0.55) | PPARGPPARASLC6A4 | |
| SCHEMBL9726215 | 0.72 | PPARG (0.48) | PPARGPPARA | |
| SCHEMBL7152142 | 0.72 | SLC6A4 (0.53) | PPARGPPARASLC6A4HAO1 | |
| SCHEMBL10680432 | 0.71 | FFAR1 (0.50) | PPARGPPARASLC6A4HAO1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125711-A1 | 2 -SUBSTITUTED- 3 -PHENYLPROPIONIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT OF INFLAMMATORY BOWEL DISEASE | Albireo Ab (SE) | 2009-12-02 | — | — | EP | claimed |
| WO-2008108735-A1 | 2 -SUBSTITUTED- 3 -PHENYLPROPIONIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT OF INFLAMMATORY BOWEL DISEASE | ALBIREO AB (SE) | 2008-09-12 | — | — | WO | claimed |
| EP-2125711-A1 | 2 -SUBSTITUTED- 3 -PHENYLPROPIONIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT OF INFLAMMATORY BOWEL DISEASE | Albireo Ab (SE) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008108735-A1 | 2 -SUBSTITUTED- 3 -PHENYLPROPIONIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT OF INFLAMMATORY BOWEL DISEASE | ALBIREO AB (SE) | 2008-09-12 | — | — | WO | disclosed |