Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.79 |
| ▸ | PPARA | Q07869 | 11/20 | 0.79 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL977816 | 0.89 | PPARG (1.00) | PPARGPPARA | |
| SCHEMBL4301066 | 0.88 | PPARG (0.78) | PPARGPPARATSHRSLC6A4FFAR1 | |
| SCHEMBL23012852 | 0.83 | PPARG (0.55) | PPARGPPARASLC7A5TSHRFFAR1 | |
| SCHEMBL29691478 | 0.83 | PPARG (0.55) | PPARGPPARASLC7A5TSHRFFAR1 | |
| SCHEMBL978223 | 0.78 | PPARG (1.00) | PPARGPPARA | |
| SCHEMBL6969028 | 0.75 | PPARG (0.49) | PPARGPPARAFFAR1MAPK1 | |
| SCHEMBL27808291 | 0.74 | PPARG (0.53) | PPARGPPARATSHRACE | |
| SCHEMBL27786423 | 0.74 | PPARG (0.76) | PPARGPPARA | |
| SCHEMBL10718327 | 0.73 | AKR1B1 (0.53) | PPARGPPARATSHRFFAR1 | |
| SCHEMBL977815 | 0.72 | PPARG (0.60) | PPARGPPARASLC7A5TSHRACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125711-A1 | 2 -SUBSTITUTED- 3 -PHENYLPROPIONIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT OF INFLAMMATORY BOWEL DISEASE | Albireo Ab (SE) | 2009-12-02 | — | — | EP | claimed |
| WO-2008108735-A1 | 2 -SUBSTITUTED- 3 -PHENYLPROPIONIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT OF INFLAMMATORY BOWEL DISEASE | ALBIREO AB (SE) | 2008-09-12 | — | — | WO | claimed |