Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.33 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8047254 | 0.98 | TSHR (0.48) | TSHRALDH1A1FAAHTHRBZDHHC20 | |
| SCHEMBL6270384 | 0.98 | TSHR (0.48) | TSHRALDH1A1FAAHTHRBZDHHC20 | |
| SCHEMBL10938271 | 0.93 | TSHR (0.48) | TSHRALDH1A1FAAHTHRBZDHHC20 | |
| SCHEMBL19863304 | 0.92 | TSHR (0.43) | TSHRALDH1A1FAAHZDHHC20ZDHHC2 | |
| SCHEMBL6445618 | 0.87 | TSHR (0.43) | TSHRALDH1A1FAAHZDHHC20ZDHHC2 | |
| SCHEMBL3900120 | 0.87 | TSHR (0.43) | TSHRALDH1A1FAAHZDHHC20ZDHHC2 | |
| SCHEMBL15676823 | 0.81 | TSHR (0.38) | TSHRALDH1A1 | |
| SCHEMBL2359642 | 0.81 | TSHR (0.41) | TSHRALDH1A1FAAHTHRBZDHHC20 | |
| SCHEMBL1679600 | 0.81 | TSHR (0.41) | TSHRALDH1A1FAAHTHRBZDHHC20 | |
| SCHEMBL4655807 | 0.81 | TSHR (0.41) | TSHRALDH1A1FAAHTHRBZDHHC20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10246415-B2 | Process for preparing carbazoles | DOW GLOBAL TECHNOLOGIES LLC (US) | 2019-04-02 | — | — | US | claimed |
| EP-3303288-A1 | PROCESS FOR PREPARING CARBAZOLES | Dow Global Technologies LLC (US) | 2018-04-11 | — | — | EP | claimed |
| WO-2018013067-A1 | PROCESS FOR PREPARING CARBAZOLES | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-01-18 | — | — | WO | claimed |
| US-5292893-A | Catalytic asymmetric and non-asymmetric reduction of times and oximes using metal catalysts | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1994-03-08 | — | — | US | claimed |
| WO-2009082247-A1 | PROCESS FOR PREPARING IMMUCILLINS HAVING A METHYLENE LINK | INDUSTRIAL RESEARCH LIMITED (NZ) | 2009-07-02 | — | — | WO | disclosed |
| US-20080042127-A1 | Transition metal free coupling of highly fluorinated and non-fluorinated pi-electron systems | WATSON MARK D | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10246415-B2 | Process for preparing carbazoles | DCLK2, DCLK1, PDCD2L | TSHR 2754/4885ALDH1A1 1221/4885FAAH 4580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.