SCHEMBL6445618

SCHEMBL6445618

C=CC[Si](CC=C)(CCCC)CCCC

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.43
ALDH1A1 P00352 1/20 0.43
FAAH O00519 1/20 0.32
ZDHHC20 Q5W0Z9 1/20 0.30
ZDHHC2 Q9UIJ5 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3900120 0.95 TSHR (0.43) TSHRALDH1A1FAAHZDHHC20ZDHHC2
SCHEMBL19863304 0.95 TSHR (0.43) TSHRALDH1A1FAAHZDHHC20ZDHHC2
SCHEMBL4301149 0.87 TSHR (0.44) TSHRALDH1A1FAAHZDHHC20ZDHHC2
SCHEMBL10938271 0.85 TSHR (0.48) TSHRALDH1A1FAAHZDHHC20ZDHHC2
SCHEMBL6270384 0.85 TSHR (0.48) TSHRALDH1A1FAAHZDHHC20ZDHHC2
SCHEMBL8047254 0.85 TSHR (0.48) TSHRALDH1A1FAAHZDHHC20ZDHHC2
SCHEMBL6445479 0.83 TSHR (0.38) TSHRALDH1A1
SCHEMBL15302091 0.80 TSHR (0.40) TSHRALDH1A1FAAHZDHHC20ZDHHC2
SCHEMBL2290668 0.80 TSHR (0.40) TSHRALDH1A1FAAHZDHHC20ZDHHC2
SCHEMBL15302165 0.80 TSHR (0.40) TSHRALDH1A1FAAHZDHHC20ZDHHC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180044452-A1 CATALYST COMPOSITION FOR PREPARING CONJUGATED DIENE-BASED POLYMER AND CONJUGATED DIENE-BASED POLYMER PREPARED USING THE SAME LG CHEM, LTD. (KR) 2018-02-15 US disclosed
CN-1223617-C Isobutylene block copolymer contg. active silicon group and preparing process thereof KANEGAFUCHI CHEMICAL IND (JP) 2005-10-19 CN disclosed
EP-0921157-B1 Alkenyl-containing isobutylene group block copolymer and process for producing it KANEKA CORP (JP) 2005-10-05 EP disclosed
CN-1420131-A Isobutylene block copolymer contg. active silicon group and preparing process thereof KANEGAFUCHI CHEMICAL IND (JP) 2003-05-28 CN disclosed
CN-1097600-C Alkenyl-containing isobutylene block copolymer and process for producing the same KANEGAFUCHI CHEMICAL IND (JP) 2003-01-01 CN disclosed
US-6348546-B2 CONTAINING HIGHLY REACTIVE GROUP; SYNTHESIS OF REACTIVE-SILICON-GROUP-CONTAINING BLOCK COPOLYMER; ELASTICITY, FLEXIBILITY, IMPACT RESISTANCE KANEKA CORPORATION (JP) 2002-02-19 US disclosed
US-20010007002-A1 Alkenyl-containing isobutylene group block copolymer and process for producing it KANEKA CORPORATION (JP) 2001-07-05 US disclosed
US-6218475-B1 HIGHLY REACTIVE PREFERABLY TERMINAL ALKENYL GROUP KANEKA CORPORATION (JP) 2001-04-17 US disclosed
CN-1223269-A Alkenyl-containing isobutylene block copolymer and process for producing the same KANEGAFUCHI CHEMICAL IND (JP) 1999-07-21 CN disclosed
EP-0921157-A1 Alkenyl-containing isobutylene group block copolymer and process for producing it KANEKA CORPORATION (JP) 1999-06-09 EP disclosed