Aes-103

Aes-103

SCHEMBL4301696

O=Cc1ccc(CO)o1.OCCOCCO

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.76
TSHR P16473 2/20 0.76
TDP1 Q9NUW8 3/20 0.38
G6PC1 P35575 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.35
HTT P42858 1/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
NPC1 O15118 2/20 0.35
MAPT P10636 2/20 0.35
RAB9A P51151 2/20 0.35
STAT1 P42224 1/20 0.35
MAPK1 P28482 1/20 0.34
GAA P10253 1/20 0.34
KDM4E B2RXH2 3/20 0.33
POLB P06746 3/20 0.33
TP53 P04637 1/20 0.33
HPGD P15428 1/20 0.33
HSP90AA1 P07900 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aes-103 SCHEMBL4301948 0.90 ALDH1A1 (0.71) ALDH1A1TSHRTDP1G6PC1L3MBTL1
Aes-103 SCHEMBL4300664 0.87 ALDH1A1 (0.67) ALDH1A1TSHRTDP1G6PC1L3MBTL1
Aes-103 SCHEMBL31307749 0.87
SCHEMBL18066379 0.87 ALDH1A1 (0.56) ALDH1A1TSHRTDP1L3MBTL1HTT
SCHEMBL4299568 0.86 ALDH1A1 (0.59) ALDH1A1TSHRTDP1L3MBTL1HTT
Aes-103 SCHEMBL17872171 0.85 ALDH1A1 (0.96) ALDH1A1TSHRTDP1G6PC1L3MBTL1
Aes-103 SCHEMBL29399464 0.85 ALDH1A1 (0.96) ALDH1A1TSHRTDP1G6PC1L3MBTL1
Aes-103 SCHEMBL31307061 0.85 ALDH1A1 (0.96) ALDH1A1TSHRTDP1G6PC1L3MBTL1
Aes-103 SCHEMBL28986200 0.85 ALDH1A1 (0.96) ALDH1A1TSHRTDP1G6PC1L3MBTL1
Aes-103 SCHEMBL29742366 0.85 ALDH1A1 (0.96) ALDH1A1TSHRTDP1G6PC1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2033958-A1 Hydroxymethylfurfural ethers from sugars and di- and triols Furanix Technologies B.V (NL) 2009-03-11 EP claimed