Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 18/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3843878 | 1.00 | KCNH2 (0.71) | KCNH2 | |
| Hydrochloric Acid SCHEMBL4299642 | 0.99 | KCNH2 (0.70) | KCNH2 | |
| Hydrochloric Acid SCHEMBL4299649 | 0.99 | KCNH2 (0.70) | KCNH2 | |
| SCHEMBL12047226 | 0.94 | KCNH2 (0.63) | KCNH2 | |
| SCHEMBL4304877 | 0.94 | KCNH2 (0.68) | KCNH2 | |
| SCHEMBL12046913 | 0.94 | KCNH2 (0.68) | KCNH2 | |
| Hydrochloric Acid SCHEMBL4299121 | 0.94 | KCNH2 (0.68) | KCNH2 | |
| SCHEMBL12046860 | 0.91 | KCNH2 (0.75) | KCNH2 | |
| SCHEMBL12046817 | 0.88 | KCNH2 (0.71) | KCNH2 | |
| Benzoic Acid SCHEMBL4294820 | 0.88 | KCNH2 (0.61) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090270374-A1 | DERIVATIVES AND ANALOGS OF N-ETHYLQUINOLONES AND N-ETHYLAZAQUINOLONES | GLAXO GROUP LIMITED (GB) | 2009-10-29 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270374-A1 | DERIVATIVES AND ANALOGS OF N-ETHYLQUINOLONES AND N-ETHYLAZAQUINOLONES | ETFA, NQO2, GNAQ | KCNH2 2142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.