Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | CCR1 | P32246 | 3/20 | 0.64 |
| ▸ | CCR5 | P51681 | 3/20 | 0.64 |
| ▸ | CCR8 | P51685 | 3/20 | 0.64 |
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | MMP2 | P08253 | 2/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.64 |
| ▸ | GMNN | O75496 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | MMP9 | P14780 | 1/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.64 |
| ▸ | MMP8 | P22894 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenanthroline SCHEMBL6532131 | 0.98 | LMNA (0.67) | LMNAKDM4ETDP1MAPTCCR1 | |
| Phenanthroline SCHEMBL28678031 | 0.92 | LMNA (0.59) | LMNAKDM4ETDP1MAPTCCR1 | |
| SCHEMBL5575762 | 0.88 | LMNA (0.50) | LMNAKDM4ETDP1MAPTCCR1 | |
| Phenanthroline SCHEMBL29531794 | 0.88 | MAPT (0.53) | LMNAKDM4ETDP1MAPTCCR1 | |
| Phenanthroline SCHEMBL1654304 | 0.88 | MAPT (0.53) | LMNAKDM4ETDP1MAPTCCR1 | |
| Phenanthroline SCHEMBL12478329 | 0.88 | LMNA (0.53) | LMNAKDM4ETDP1MAPTCCR1 | |
| 1-Naphthoquinoline SCHEMBL27916826 | 0.87 | LMNA (0.55) | LMNAKDM4ETDP1MAPTCCR1 | |
| SCHEMBL28304874 | 0.83 | KDM4E (0.47) | LMNAKDM4ETDP1MAPTCCR1 | |
| Phenanthroline SCHEMBL1237621 | 0.82 | CCR1 (0.94) | LMNAKDM4ETDP1MAPTCCR1 | |
| Phenanthroline SCHEMBL1270937 | 0.82 | CCR1 (0.94) | LMNAKDM4ETDP1MAPTCCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013040100-A1 | ELECTROLYTE MATERIALS FOR BATTERIES AND METHODS FOR USE | WILDCAT DISCOVERY TECHNOLOGIES, INC. (US) | 2013-03-21 | — | — | WO | disclosed |
| WO-2009125873-A1 | FUSED RING COMPOUNDS AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-15 | — | — | WO | disclosed |