Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C8 | P10632 | 1/20 | 0.64 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | EBP | Q15125 | 2/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | EBPL | Q9BY08 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3013499 | 0.82 | CYP2C8 (0.56) | CYP2C8S1PR1KDM4EALDH1A1HPGD | |
| SCHEMBL12544517 | 0.82 | CYP2C8 (0.56) | CYP2C8S1PR1KDM4EALDH1A1HPGD | |
| SCHEMBL3015559 | 0.79 | CYP2C8 (0.78) | CYP2C8S1PR1KDM4EALOX5ABCB1 | |
| SCHEMBL30992329 | 0.79 | CYP2C8 (1.00) | CYP2C8S1PR1KDM4EALOX5ABCB1 | |
| SCHEMBL3002082 | 0.79 | CYP2C8 (1.00) | CYP2C8S1PR1KDM4EALOX5ABCB1 | |
| SCHEMBL4002128 | 0.77 | CYP2C8 (0.76) | CYP2C8KDM4EALOX5ABCB1ALDH1A1 | |
| SCHEMBL3013908 | 0.76 | CYP2C8 (0.86) | CYP2C8KDM4EALOX5ABCB1ALDH1A1 | |
| SCHEMBL3010742 | 0.76 | CYP2C8 (0.74) | CYP2C8KDM4EALOX5ABCB1ALDH1A1 | |
| SCHEMBL4145033 | 0.76 | CYP2C8 (0.73) | CYP2C8S1PR1ALOX5MAOBPTGES | |
| SCHEMBL3010121 | 0.75 | KMT2A (0.53) | CYP2C8S1PR1KDM4EALOX5MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069321-A1 | NOVEL BENZOFURAN TYPE DERIVATIVES, A COMPOSITION COMPRISING THE SAME FOR TREATING OR PREVENTING COGNITIVE DYSFUNCTION AND THE USE THEREOF | Digital Biotech Co., Ltd. (KR) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008041826-A1 | NOVEL BENZOFURAN TYPE DERIVATIVES, A COMPOSITION COMPRISING THE SAME FOR TREATING OR PREVENTING COGNITIVE DYSFUNCTION AND THE USE THEREOF | DIGITAL BIOTECH CO., LTD (KR) | 2008-04-10 | — | — | WO | disclosed |