Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC1 | P19801 | 2/20 | 0.53 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.53 |
| ▸ | KDM4C | Q9H3R0 | 11/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.50 |
| ▸ | KDM6B | O15054 | 5/20 | 0.48 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 2/20 | 0.41 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30545160 | 0.87 | SIRT3 (0.54) | AOC1AOC3KDM4CTDP1SIRT3 | |
| SCHEMBL15110277 | 0.87 | SIRT3 (0.54) | AOC1AOC3KDM4CTDP1SIRT3 | |
| Hydrochloric Acid SCHEMBL28283002 | 0.85 | SIRT3 (0.53) | AOC1AOC3KDM4CTDP1SIRT3 | |
| SCHEMBL15286961 | 0.85 | KDM4C (0.70) | AOC1AOC3KDM4CKDM6BKDM4E | |
| SCHEMBL17723987 | 0.81 | KDM4C (0.71) | AOC1AOC3KDM4CTDP1SIRT3 | |
| SCHEMBL18421265 | 0.75 | KDM4C (0.51) | KDM4CTDP1SIRT3KDM6BIRAK4 | |
| SCHEMBL9215519 | 0.75 | TDP1 (0.53) | KDM4CTDP1SIRT3KDM6BKDM4E | |
| SCHEMBL9210426 | 0.75 | TDP1 (0.53) | KDM4CTDP1SIRT3KDM6BKDM4E | |
| SCHEMBL2104582 | 0.75 | KDM4E (0.50) | IRAK4KDM4EALDH1A1MEN1MAPT | |
| SCHEMBL21543646 | 0.75 | JAK1 (0.49) | KDM4CTDP1SIRT3KDM6BIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009130015-A1 | IMPROVED RAF INHIBITORS | GPC BIOTECH AG (DE) | 2009-10-29 | — | — | WO | disclosed |