Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KDM5A | P29375 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.40 |
| ▸ | KDM6B | O15054 | 2/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9210426 | 0.94 | TDP1 (0.53) | TDP1SIRT3KDM4EALDH1A1GLA | |
| SCHEMBL24997725 | 0.80 | KDM5A (0.45) | TDP1SIRT3KDM4EALDH1A1GLA | |
| SCHEMBL13162021 | 0.80 | SIRT3 (0.56) | TDP1SIRT3KDM4EALDH1A1GLA | |
| SCHEMBL22190223 | 0.80 | TDP1 (0.55) | TDP1SIRT3KDM4EALDH1A1GLA | |
| SCHEMBL31678729 | 0.79 | KDM4C (0.51) | KDM4EALDH1A1GLAGAAKDM5A | |
| SCHEMBL8485471 | 0.79 | ROCK2 (0.59) | KDM5AALOX5CHRM2GRM5SIGMAR1 | |
| SCHEMBL24568249 | 0.79 | PREP (0.55) | KDM4EALDH1A1GLAGAAKDM5A | |
| SCHEMBL1687197 | 0.78 | TDP1 (0.67) | TDP1SIRT3KDM4EALDH1A1GLA | |
| SCHEMBL1330970 | 0.78 | TDP1 (0.67) | TDP1SIRT3KDM4EALDH1A1GLA | |
| SCHEMBL3890104 | 0.78 | ALDH1A1 (0.67) | TDP1SIRT3KDM4EALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422456-B1 | Pyridine derivatives and their use in combating unwanted plant growth | BASF AG (DE) | 1995-05-03 | — | — | EP | claimed |