Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | SPR | P35270 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12516306 | 0.90 | NPC1 (0.44) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL2221780 | 0.81 | KDM4E (0.47) | KMT2AALDH1A1KDM4E | |
| SCHEMBL29829548 | 0.79 | BRS3 (0.38) | KMT2AALDH1A1KDM4EEGLN1 | |
| SCHEMBL15746728 | 0.79 | BRS3 (0.38) | KMT2AALDH1A1KDM4EEGLN1 | |
| SCHEMBL1503149 | 0.79 | KMT2A (0.48) | NPC1RAB9AKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL1503237 | 0.76 | KMT2A (0.45) | KMT2AMAPTGAAALDH1A1KDM4E | |
| SCHEMBL1503172 | 0.76 | KDM4E (0.45) | NPC1RAB9AKMT2ASMN1; SMN2GAA | |
| SCHEMBL27833103 | 0.75 | KDM4E (0.46) | KMT2AALDH1A1KDM4E | |
| SCHEMBL22283906 | 0.75 | KDM4E (0.37) | KMT2AMAPTALDH1A1KDM4EEGLN1 | |
| SCHEMBL4306646 | 0.74 | HCAR2 (0.35) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146555-A1 | HIV INTEGRASE INHIBITORS FROM PYRIDOXINE | AMBRILIA BIOPHARMA INC. (CA) | 2009-12-10 | — | — | WO | claimed |