Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.33 |
| ▸ | BRS3 | P32247 | 1/20 | 0.32 |
| ▸ | ME2 | P23368 | 1/20 | 0.32 |
| ▸ | ME1 | P48163 | 1/20 | 0.32 |
| ▸ | ME3 | Q16798 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15746657 | 0.90 | KDM4E (0.41) | NR4A2KDM5AKDM4CKDM5BXDH | |
| SCHEMBL1503195 | 0.89 | HCAR2 (0.36) | HCAR2FFAR1FFAR4KMT2A | |
| SCHEMBL15746728 | 0.86 | BRS3 (0.38) | FFAR1KDM5AKDM4CKDM5BKMT2A | |
| SCHEMBL29829548 | 0.86 | BRS3 (0.38) | FFAR1KDM5AKDM4CKDM5BKMT2A | |
| SCHEMBL15746710 | 0.82 | NR4A2 (0.45) | NR4A2FFAR1FFAR4KDM4CALKBH1 | |
| SCHEMBL15746784 | 0.81 | BCHE (0.37) | KMT2A | |
| SCHEMBL15746685 | 0.81 | ALKBH1 (0.42) | KDM5AKDM4CKDM5BALKBH1 | |
| SCHEMBL2221780 | 0.80 | KDM4E (0.47) | KMT2AP4HTM | |
| SCHEMBL15746652 | 0.80 | MAOB (0.38) | KDM5AKDM4CKDM5B | |
| SCHEMBL28791544 | 0.79 | L3MBTL1 (0.42) | HCAR2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146555-A1 | HIV INTEGRASE INHIBITORS FROM PYRIDOXINE | AMBRILIA BIOPHARMA INC. (CA) | 2009-12-10 | — | — | WO | claimed |
| US-8742123-B2 | HIV integrase inhibitors from pyridoxine | TAIMED BIOLOGICS, INC. (TW) | 2014-06-03 | — | — | US | disclosed |