⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4296787 | 0.85 | GRM1 (0.30) | — | |
| SCHEMBL4303289 | 0.83 | GPR183 (0.32) | — | |
| SCHEMBL4294463 | 0.82 | KDM4E (0.32) | — | |
| SCHEMBL4308749 | 0.79 | — | — | |
| SCHEMBL4307714 | 0.79 | SLC6A2 (0.32) | — | |
| SCHEMBL4294477 | 0.76 | CDK5 (0.32) | — | |
| SCHEMBL2937487 | 0.75 | — | — | |
| SCHEMBL4294432 | 0.73 | — | — | |
| SCHEMBL4307231 | 0.71 | ALDH1A1 (0.35) | — | |
| SCHEMBL3278567 | 0.71 | GBA1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8071592-B2 | Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones | GLAXO GROUP LIMITED (GB) | 2011-12-06 | — | — | US | disclosed |
| US-20090270374-A1 | DERIVATIVES AND ANALOGS OF N-ETHYLQUINOLONES AND N-ETHYLAZAQUINOLONES | GLAXO GROUP LIMITED (GB) | 2009-10-29 | — | — | US | disclosed |