Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.52 |
| ▸ | HTR1D | P28221 | 10/20 | 0.51 |
| ▸ | HTR1B | P28222 | 9/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.51 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26078505 | 0.83 | TAAR1 (0.56) | TAAR1HTR1DHTR1BADRA2AADRA2B | |
| SCHEMBL26078605 | 0.76 | HTR1D (0.48) | TAAR1HTR1DHTR1BADRA2AADRA2B | |
| SCHEMBL26078594 | 0.76 | HTR1D (0.48) | TAAR1HTR1DHTR1BADRA2AADRA2B | |
| SCHEMBL26078611 | 0.76 | HTR1D (0.48) | TAAR1HTR1DHTR1BADRA2AADRA2B | |
| SCHEMBL26078608 | 0.76 | HTR1D (0.48) | TAAR1HTR1DHTR1BADRA2AADRA2B | |
| SCHEMBL26078507 | 0.75 | HTR1D (0.57) | TAAR1HTR1DHTR1BADRA2AADRA2B | |
| SCHEMBL26078509 | 0.74 | HTR1D (0.49) | TAAR1HTR1DHTR1BADRA2AADRA2B | |
| SCHEMBL26078561 | 0.73 | HTR1D (0.76) | TAAR1HTR1DHTR1BADRA2AADRA2B | |
| SCHEMBL26078452 | 0.72 | HTR1D (0.68) | TAAR1HTR1DHTR1BADRA2AADRA2B | |
| SCHEMBL26078499 | 0.72 | ADRA2C (0.46) | TAAR1HTR1DHTR1BADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2009256240-A | IMIDAZOLINE DERIVATIVE | UNIV OF FUKUI | 2009-11-05 | — | — | JP | disclosed |
| WO-2009128479-A1 | IMIDAZOLINE DERIVATIVE | 日本ケミファ株式会社 (JP) | 2009-10-22 | — | — | WO | disclosed |