Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 3/20 | 0.35 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9391104 | 0.91 | LMNA (0.52) | KMT2ANPSR1SMN1; SMN2LMNAMAPT | |
| SCHEMBL11617315 | 0.87 | CACNA2D1 (0.33) | KMT2ACACNA2D1TLR8TLR7 | |
| SCHEMBL9861502 | 0.87 | CACNA2D1 (0.33) | KMT2ACACNA2D1NPSR1MEN1 | |
| SCHEMBL39223 | 0.87 | KMT2A (0.47) | KMT2ACACNA2D1SMN1; SMN2LMNAPDE4A | |
| SCHEMBL10603018 | 0.87 | TLR8 (0.38) | CACNA2D1TLR8TLR7 | |
| SCHEMBL10444895 | 0.76 | KMT2A (0.36) | KMT2ASMN1; SMN2LMNAPDE4ACYP1A2 | |
| SCHEMBL16411475 | 0.74 | SMN1; SMN2 (0.33) | KMT2ANPSR1SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL21162636 | 0.74 | TLR8 (0.37) | CACNA2D1SMN1; SMN2LMNAALDH1A1CYP1A2 | |
| SCHEMBL18027898 | 0.72 | PDE4A (0.63) | KMT2ANPSR1SMN1; SMN2LMNAMAPT | |
| SCHEMBL16411406 | 0.72 | AKT1 (0.35) | NPSR1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009135813-A1 | DEGRADABLE MATERIAL | BASF SE (DE) | 2009-11-12 | — | — | WO | disclosed |