Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL430365 | 1.00 | TRPA1 (0.33) | TRPA1 | |
| SCHEMBL12841313 | 0.87 | KCNH2 (0.32) | TRPA1 | |
| SCHEMBL7199552 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL22771766 | 0.84 | KCNH2 (0.32) | — | |
| Hydrochloric Acid SCHEMBL22771765 | 0.84 | KCNH2 (0.32) | — | |
| Hydrochloric Acid SCHEMBL22771780 | 0.80 | KCNH2 (0.30) | — | |
| Hydrochloric Acid SCHEMBL22771779 | 0.80 | KCNH2 (0.30) | — | |
| SCHEMBL22575303 | 0.78 | KCNH2 (0.43) | — | |
| SCHEMBL12737718 | 0.76 | — | — | |
| SCHEMBL5509562 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8334412-B2 | Process for preparing 3-(methylthio)propanal | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-12-18 | — | — | US | disclosed |
| US-8173845-B2 | Process for producing 3-methylthiopropanal | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-05-08 | — | — | US | disclosed |
| US-20120022295-A1 | PROCESS FOR PREPARING 3-(METHYLTHIO)PROPANAL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-01-26 | — | — | US | disclosed |
| EP-2239252-B1 | Process for producing 3-methylthiopropanal | SUMITOMO CHEMICAL CO (JP) | 2011-10-19 | — | — | EP | disclosed |
| EP-2239252-A1 | Process for producing 3-methylthiopropanal | Sumitomo Chemical Company, Limited (JP) | 2010-10-13 | — | — | EP | disclosed |
| US-20100256419-A1 | PROCESS FOR PRODUCING 3-METHYLTHIOPROPANAL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256419-A1 | PROCESS FOR PRODUCING 3-METHYLTHIOPROPANAL | MGMT, TPMT, PTMA | TRPA1 27/4885 |
| US-20120022295-A1 | PROCESS FOR PREPARING 3-(METHYLTHIO)PROPANAL | PTMA, TMT1A, MGMT | TRPA1 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.