Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 4/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | CA7 | P43166 | 4/20 | 0.48 |
| ▸ | CA9 | Q16790 | 4/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1707844 | 0.85 | CYP3A4 (0.45) | TSHRCYP3A4MEN1MAPTMAPK10 | |
| SCHEMBL20763545 | 0.77 | TSHR (0.59) | TSHRCYP3A4MEN1USP2CYP1A2 | |
| SCHEMBL574192 | 0.76 | TSHR (0.68) | TSHRCYP3A4MEN1USP2CYP1A2 | |
| SCHEMBL30968707 | 0.76 | TSHR (0.68) | TSHRCYP3A4MEN1USP2CYP1A2 | |
| SCHEMBL23689805 | 0.76 | TSHR (0.62) | TSHRCYP3A4MEN1USP2CYP1A2 | |
| SCHEMBL23925917 | 0.75 | TSHR (0.53) | TSHRCYP3A4MAPTALOX15CA12 | |
| SCHEMBL1235309 | 0.75 | CA12 (0.67) | TSHRCYP3A4MEN1USP2CYP1A2 | |
| Ammonia Solution, Strong SCHEMBL29087129 | 0.75 | TSHR (0.66) | TSHRCYP3A4MEN1USP2CYP1A2 | |
| SCHEMBL29617021 | 0.72 | TSHR (0.80) | TSHRCYP3A4MEN1USP2CYP1A2 | |
| SCHEMBL3683272 | 0.72 | TSHR (0.80) | TSHRCYP3A4MEN1USP2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2011788-A1 | OXADIAZOLIDINEDIONE COMPOUND | Astellas Pharma Inc. (JP) | 2009-01-07 | — | — | EP | disclosed |