SCHEMBL3683272

SCHEMBL3683272

CCOC(=O)c1ccccc1-c1ccccc1C(=O)OCC

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.80
HSD17B10 Q99714 4/20 0.67
ALDH1A1 P00352 3/20 0.67
CYP3A4 P08684 2/20 0.59
KMT2A Q03164 2/20 0.59
MAPT P10636 2/20 0.59
MEN1 O00255 1/20 0.59
USP2 O75604 1/20 0.59
CYP1A2 P05177 1/20 0.59
CYP2C9 P11712 1/20 0.59
ALOX15 P16050 1/20 0.59
CYP2C19 P33261 1/20 0.59
MAPK10 P53779 1/20 0.59
PTK2B Q14289 1/20 0.59
NCOA1 Q15788 1/20 0.59
NCOA3 Q9Y6Q9 1/20 0.59
CDC25B P30305 2/20 0.56
PDK2 Q15119 1/20 0.54
TDP1 Q9NUW8 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29617021 1.00 TSHR (0.80) TSHRHSD17B10ALDH1A1CYP3A4KMT2A
SCHEMBL3950053 0.93 TSHR (0.69) TSHRHSD17B10ALDH1A1CYP3A4KMT2A
SCHEMBL8075091 0.93 TSHR (0.69) TSHRHSD17B10ALDH1A1CYP3A4KMT2A
SCHEMBL5572323 0.93 TSHR (0.69) TSHRHSD17B10ALDH1A1CYP3A4KMT2A
SCHEMBL4320539 0.91 TSHR (0.67) TSHRHSD17B10ALDH1A1CYP3A4KMT2A
SCHEMBL16415690 0.89 TSHR (0.65) TSHRHSD17B10ALDH1A1CYP3A4KMT2A
SCHEMBL5096210 0.89 TSHR (0.65) TSHRHSD17B10ALDH1A1CYP3A4KMT2A
Diethyl Phthalate SCHEMBL29404255 0.89 TSHR (1.00) TSHRHSD17B10ALDH1A1CYP3A4KMT2A
Diethyl Phthalate SCHEMBL22296 0.89 TSHR (1.00) TSHRHSD17B10ALDH1A1CYP3A4KMT2A
Diethyl Phthalate SCHEMBL5306972 0.89 TSHR (1.00) TSHRHSD17B10ALDH1A1CYP3A4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114573956-A Preparation method of nano magnesium hydroxide modified degradable copolyester 浙江恒逸石化研究院有限公司 2022-06-03 CN claimed
CN-114573956-A Preparation method of nano magnesium hydroxide modified degradable copolyester 浙江恒逸石化研究院有限公司 2022-06-03 CN disclosed
CN-112500569-B Polyimide precursor composition, polyimide film, laminated film, and display device 武汉柔显科技股份有限公司 2021-05-25 CN disclosed
US-11001650-B2 Electron donor for polyolefin polymerization catalysts and uses thereof BRASKEM AMERICA, INC. (US) 2021-05-11 US disclosed
CN-112500569-A Polyimide precursor composition, polyimide film, laminated film, and display device 武汉柔显科技股份有限公司 2021-03-16 CN disclosed
EP-1472293-B1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2017-04-26 EP disclosed
WO-2017027710-A1 ELECTRON DONOR FOR POLYOLEFIN POLYMERIZATION CATALYSTS AND USES THEREOF W.R. GRACE & CO.-CONN. (US) 2017-02-16 WO disclosed
CN-105566518-A Catalyst component for olefin polymerization, preparation method thereof and catalyst CHINA PETROLEUM & CHEM CORP 2016-05-11 CN disclosed
CN-105504109-A Catalyst component for alkene polymerization and catalyst thereof CHINA PETROLEUM & CHEM CORP 2016-04-20 CN disclosed
US-7781540-B2 Resin composition and molded articles thereof OSAKA GAS CO., LTD. (JP) 2010-08-24 US disclosed
EP-1472293-A4 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEMICAL (CN) 2008-01-16 EP disclosed
EP-1808461-A1 RESIN COMPOSITION AND MOLDED OBJECT THEREOF Teijin Chemicals, Ltd. (JP) 2007-07-18 EP disclosed
EP-1478617-A4 POLYOL ESTER COMPOUNDS USEFUL IN PREPARATION OF A CATALYST FOR OLEFINS POLYMERIZATION, PROCESS FOR PREPARING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEMICAL (CN) 2006-04-19 EP disclosed
US-20050239636-A1 Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2005-10-27 US disclosed
US-20050096389-A1 Polyol ester compounds useful in preparation of a catalyst for olefins polymerization, process for preparing the same and use thereof CHINA PETROLEUM & CHEMICAL (CN) 2005-05-05 US disclosed
EP-1478617-A1 POLYOL ESTER COMPOUNDS USEFUL IN PREPARATION OF A CATALYST FOR OLEFINS POLYMERIZATION, PROCESS FOR PREPARING THE SAME AND USE THEREOF China Petroleum & Chemical Corporation (CN) 2004-11-24 EP disclosed
EP-1472293-A1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF China Petroleum & Chemical Corporation (CN) 2004-11-03 EP disclosed
WO-2003068828-A1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2003-08-21 WO disclosed
WO-2003068723-A1 POLYOL ESTER COMPOUNDS USEFUL IN PREPARATION OF A CATALYST FOR OLEFINS POLYMERIZATION, PROCESS FOR PREPARING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2003-08-21 WO disclosed
US-4066638-A WATER-SOLUBLE FIBER REACTIVE PHENYL-AZO-NAPHTHYL DYESTUFFS CONTAINING TWO SULFO GROUPS IN THE PHENYL MOIETY HOECHST AKTIENGESELLSCHAFT (DT) 1978-01-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050096389-A1 Polyol ester compounds useful in preparation of a catalyst for olefins polymerization, process for preparing the same and use thereof CBR3, CBR1, OXER1 TSHR 921/4885HSD17B10 1112/4885ALDH1A1 3489/4885
US-11001650-B2 Electron donor for polyolefin polymerization catalysts and uses thereof PARG, PUF60, PARP1 TSHR 4883/4885HSD17B10 1997/4885ALDH1A1 791/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.