Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 5/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2302055 | 0.93 | CYP2C9 (0.56) | CYP2C9CYP3A4CYP2C19KCNH2CYP2C8 | |
| SCHEMBL4310928 | 0.89 | CYP2C9 (0.54) | CYP2C9CYP3A4CYP2C19KCNH2CYP2C8 | |
| SCHEMBL6119957 | 0.88 | CYP2C9 (0.54) | CYP2C9CYP3A4CYP2C19KCNH2CYP2C8 | |
| SCHEMBL2298808 | 0.87 | CYP2C9 (0.59) | CYP2C9CYP3A4CYP2C19KCNH2 | |
| SCHEMBL4605501 | 0.87 | CYP2C9 (0.53) | CYP2C9CYP3A4CYP2C19KCNH2CYP2C8 | |
| SCHEMBL14697885 | 0.86 | CYP2C9 (0.55) | CYP2C9CYP3A4CYP2C19KCNH2CYP2C8 | |
| SCHEMBL14697709 | 0.85 | CYP2C9 (0.55) | CYP2C9CYP3A4CYP2C19KCNH2CYP2C8 | |
| SCHEMBL6118746 | 0.85 | CYP2C9 (0.54) | CYP2C9CYP3A4CYP2C19KCNH2CYP2C8 | |
| SCHEMBL4314359 | 0.85 | CYP3A4 (0.55) | CYP2C9CYP3A4CYP2C19KCNH2CYP2C8 | |
| SCHEMBL14697997 | 0.84 | CYP2C9 (0.56) | CYP2C9CYP3A4CYP2C19KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137500-A1 | 6-SUBSTITUTED BENZOFURAN COMPOUNDS TO TREAT INFECTION WITH HEPATITIS C VIRUS | WYETH (US) | 2009-11-12 | — | — | WO | claimed |
| WO-2009137500-A1 | 6-SUBSTITUTED BENZOFURAN COMPOUNDS TO TREAT INFECTION WITH HEPATITIS C VIRUS | WYETH (US) | 2009-11-12 | — | — | WO | disclosed |