Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 8/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.63 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.63 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.63 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.63 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.63 |
| ▸ | SCN1A | P35498 | 3/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.63 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.63 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | SLC22A2 | O15244 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.63 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL19100311 | 0.96 | KDM4E (0.66) | CYP2D6KDM4EALDH1A1SLC22A1ABCB11 | |
| SCHEMBL669873 | 0.90 | CYP2D6 (0.64) | CYP2D6KDM4EALDH1A1SLC22A1ABCB11 | |
| SCHEMBL1612723 | 0.90 | CYP2D6 (0.60) | CYP2D6KDM4EALDH1A1SLC22A1ABCB11 | |
| SCHEMBL22862890 | 0.88 | KDM4E (0.66) | CYP2D6KDM4EALDH1A1SLC22A1ABCB11 | |
| SCHEMBL9614099 | 0.87 | CYP2D6 (0.57) | CYP2D6KDM4EALDH1A1SLC22A1ABCB11 | |
| SCHEMBL15239796 | 0.87 | KDM4E (0.64) | CYP2D6KDM4EALDH1A1SLC22A1ABCB11 | |
| SCHEMBL789401 | 0.86 | KDM4E (0.59) | CYP2D6KDM4EALDH1A1SLC22A1ABCB11 | |
| SCHEMBL5611090 | 0.85 | CYP2D6 (0.58) | CYP2D6KDM4EALDH1A1SLC22A1ABCB11 | |
| SCHEMBL2150774 | 0.84 | KDM4E (0.61) | CYP2D6KDM4EALDH1A1SLC22A1ABCB11 | |
| SCHEMBL4278098 | 0.84 | CYP2D6 (0.65) | CYP2D6KDM4EALDH1A1SLC22A1ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3829569-B1 | SPINOSYN FORMULATIONS FOR USE IN THE TREATMENT OF DEMODEX-INDUCED OCULAR CONDITIONS | APERTA BIOSCIENCES LLC (US) | 2025-09-03 | — | — | EP | claimed |
| CN-120166987-A | Phthalazine derivatives as pyruvate kinase modulators | 西特瑞治疗有限公司 | 2025-06-17 | — | — | CN | claimed |
| US-20240390375-A1 | METHODS AND COMPOSITIONS FOR TREATING VIRAL OR VIRALLY-INDUCED CONDITIONS | Viracta Subsidiary, Inc. (US) | 2024-11-28 | — | — | US | claimed |
| US-20240287136-A1 | PHARMACEUTICAL COMPOSITION AND THE USE THEREOF IN THE TREATMENT OF AUTOIMMUNE DISEASES | SINGAPORE HEALTH SERVICES PTE. LTD. (SG) | 2024-08-29 | — | — | US | claimed |
| CN-118317951-A | Phthalazine derivatives as pyruvate kinase modulators | 西特瑞治疗有限公司 | 2024-07-09 | — | — | CN | claimed |
| EP-4340884-A1 | TREATMENT OF INFECTIONS IN AND AROUND THE EYE | University of Miami (US) | 2024-03-27 | — | — | EP | claimed |
| US-20230233576-A1 | ECLITASERTIB FOR USE IN TREATING CONDITIONS INVOLVING SYSTEMIC HYPERINFLAMMATORY RESPONSE | GENZYME CORPORATION | 2023-07-27 | — | — | US | claimed |
| CN-116367828-A | Antiviral pharmaceutical composition containing targeting nanoparticles and having synergistic effect | 新科生医股份有限公司 | 2023-06-30 | — | — | CN | claimed |
| EP-4135705-A1 | ECLITASERTIB FOR USE IN TREATING CONDITIONS INVOLVING SYSTEMIC HYPERINFLAMMATORY RESPONSE | GENZYME CORPORATION (US) | 2023-02-22 | — | — | EP | claimed |
| WO-2022245950-A1 | TREATMENT OF INFECTIONS IN AND AROUND THE EYE | UNIVERSITY OF MIAMI (US) | 2022-11-24 | — | — | WO | claimed |
| EP-2200607-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | Calcimedica, Inc. (US) | 2010-06-30 | — | — | EP | claimed |
| WO-2010034003-A2 | BENZYLTHIOTETRAZOLE INHIBITORS OF STORE OPERATED CALCIUM RELEASE | CALCIMEDICA, INC. (US) | 2010-03-25 | — | — | WO | claimed |
| WO-2010034011-A2 | PHENYLTHIOPHENYLDIHYDROBENZOTHIAZEPINE INHIBITORS OF STORE OPERATED CALCIUM RELEASE | CALCIMEDICA, INC. (US) | 2010-03-25 | — | — | WO | claimed |
| WO-2009129335-A2 | SELECTIVE INHIBITORS OF HISTONE DEACETYLASE | PHARMACYCLICS, INC. (US) | 2009-10-22 | — | — | WO | claimed |
| WO-2009076454-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA, INC. (US) | 2009-06-18 | — | — | WO | claimed |
| WO-2009035818-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA, INC. (US) | 2009-03-19 | — | — | WO | claimed |
| WO-2007109178-A9 | INDOLE DERIVATIVES AS INHIBITORS OF HISTONE DEACETYLASE | PHARMACYCLICS INC (US) | 2008-10-16 | — | — | WO | claimed |
| WO-2008061160-A1 | USES OF SELECTIVE INHIBITORS OF HDAC8 FOR TREATMENT OF INFLAMMATORY CONDITIONS | PHARMACYCLICS, INC. (US) | 2008-05-22 | — | — | WO | claimed |
| US-20070281934-A1 | INDOLE DERIVATIVES AS INHIBITORS OF HISTONE DEACETYLASE | PHARMACYCLICS, INC. (US) | 2007-12-06 | — | — | US | claimed |
| WO-2007109178-A2 | INDOLE DERIVATIVES AS INHIBITORS OF HISTONE DEACETYLASE | PHARMACYCLICS, INC. (US) | 2007-09-27 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230233576-A1 | ECLITASERTIB FOR USE IN TREATING CONDITIONS INVOLVING SYSTEMIC HYPERINFLAMMATORY RESPONSE | RIPK1, RIPK2, RIPK3 | CYP2D6 4394/4885KDM4E 3696/4885ALDH1A1 4798/4885 |
| US-20240287136-A1 | PHARMACEUTICAL COMPOSITION AND THE USE THEREOF IN THE TREATMENT OF AUTOIMMUNE DISEASES | QPCTL, QARS1, QPCT | CYP2D6 440/4885KDM4E 40/4885ALDH1A1 1297/4885 |
| US-20070281934-A1 | INDOLE DERIVATIVES AS INHIBITORS OF HISTONE DEACETYLASE | HDAC8, HDAC1, HDAC2 | CYP2D6 4221/4885KDM4E 275/4885ALDH1A1 1362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.