SCHEMBL430581

SCHEMBL430581

Nc1c(S(=O)(=O)O)cc(Nc2ccc(S(=O)(=O)O)c(Nc3nc(Cl)nc(Cl)n3)c2)c2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGDS O60760 1/20 0.81
P2RY12 Q9H244 4/20 0.78
P2RY2 P41231 4/20 0.78
P2RX2 Q9UBL9 2/20 0.78
CHAT P28329 4/20 0.74
USP2 O75604 2/20 0.74
APEX1 P27695 2/20 0.74
ENPP3 O14638 1/20 0.72
ENPP1 P22413 1/20 0.72
P2RY4 P51582 5/20 0.68
P2RY6 Q15077 2/20 0.68
P2RX7 Q99572 1/20 0.68
P2RY1 P47900 2/20 0.64
FUT8 Q9BYC5 2/20 0.64
GNG2 P59768 3/20 0.64
GNB1 P62873 3/20 0.64
MEN1 O00255 1/20 0.61
LMNA P02545 1/20 0.61
TP53 P04637 1/20 0.61
POLB P06746 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29517169 1.00 HPGDS (0.81) HPGDSP2RY12P2RY2P2RX2CHAT
SCHEMBL11885370 0.95 HPGDS (0.77) HPGDSP2RY12P2RY2P2RX2CHAT
SCHEMBL31722681 0.94 P2RY12 (0.90) HPGDSP2RY12P2RY2P2RX2CHAT
SCHEMBL12661608 0.94 HPGDS (0.77) HPGDSP2RY12P2RY2P2RX2CHAT
SCHEMBL17000443 0.93 CHAT (0.87) HPGDSP2RY12P2RY2P2RX2CHAT
SCHEMBL13213990 0.92 HPGDS (0.91) HPGDSP2RY12P2RY2P2RX2CHAT
SCHEMBL13214132 0.92 CHAT (0.79) HPGDSP2RY12P2RY2P2RX2CHAT
SCHEMBL20694712 0.92 HPGDS (0.74) HPGDSP2RY12P2RY2P2RX2CHAT
SCHEMBL9167831 0.91 CHAT (0.87) HPGDSP2RY12P2RY2P2RX2CHAT
SCHEMBL20038647 0.91 HPGDS (0.74) HPGDSP2RY12P2RY2P2RX2CHAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1992 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260015651-A1 Solid Support for Sample Collection Global Life Sciences Solutions Operations UK Ltd (GB) 2026-01-15 US claimed
WO-2025243218-A1 METHOD FOR MAKING CENTRALLY COLORED CONTACT LENSES ALCON INC. (CH) 2025-11-27 WO claimed
US-12442032-B2 Solid support for sample collection Global Life Sciences Solutions Operations UK Ltd (GB) 2025-10-14 US claimed
EP-4603894-A1 BLUE LIGHT BLOCKING CONTACT LENSES AND PREPARATION METHOD THEREFOR Pegavision Corporation (TW) 2025-08-20 EP claimed
EP-4590429-A1 SEPARATION MEDIA AND PURIFICATION METHODS FOR CARBOHYDRATE CONTAINING MOLECULES USING THE SAME Donaldson Company, Inc. (US) 2025-07-30 EP claimed
CN-120119482-A High-dye-utilization-rate ink for ink-jet printing and preparation method thereof 青岛大学 2025-06-10 CN claimed
CN-119955328-A Preparation method and dyeing method of oligosaccharide-based macromolecular dye 武汉纺织大学 2025-05-09 CN claimed
CN-119800738-A Durable flame-retardant dyeing finishing method for cellulose-based yarns or fabrics 青岛大学 2025-04-11 CN claimed
US-12265082-B2 Detecting microbial infection in wounds SYNOVO GMBH (DE) 2025-04-01 US claimed
CN-119638918-A Colored silicon polymer material and preparation method thereof 江苏天眼医药科技股份有限公司 2025-03-18 CN claimed
CN-1090930-A Manufacturing is through the method for the contact lens that stains JOHNSON & JOHNSON VISION PROD (US) 1994-08-17 CN claimed
EP-0525073-B1 ANTHRAQUINONES AS INHIBITORS OF SULFIDE PRODUCTION FROM SULFATE-REDUCING BACTERIA DU PONT (US) 1994-05-25 EP claimed
EP-0595575-A1 Method for preparing tinted contact lens JOHNSON & JOHNSON VISION PRODUCTS, INC. (US) 1994-05-04 EP claimed
EP-0525073-A1 ANTHRAQUINONES AS INHIBITORS OF SULFIDE PRODUCTION FROM SULFATE-REDUCING BACTERIA. DU PONT (US) 1993-02-03 EP claimed
US-5100471-A Liquid ink compositions XEROX CORPORATION (US) 1992-03-31 US claimed
WO-1991015954-A1 ANTHRAQUINONES AS INHIBITORS OF SULFIDE PRODUCTION FROM SULFATE-REDUCING BACTERIA E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-10-31 WO claimed
EP-0329184-A2 Antimers and antimeric conjugation NEORX CORPORATION (US) 1989-08-23 EP claimed
US-4623625-A ZYMOMONAS LA TROBE UNIVERSITY (AU) 1986-11-18 US claimed
EP-0139705-A1 ENZYME EXTRACTION AND PURIFICATION PROCESSES LA TROBE UNIVERSITY (AU) 1985-05-08 EP claimed
WO-1984004329-A1 ENZYME EXTRACTION AND PURIFICATION PROCESSES UNIV TROBE (AU) 1984-11-08 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015651-A1 Solid Support for Sample Collection EWSR1, SETDB1, DNMT3A HPGDS 4766/4885P2RY12 4456/4885P2RY2 4231/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.