Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 9/20 | 0.89 |
| ▸ | CA2 | P00918 | 9/20 | 0.89 |
| ▸ | CA9 | Q16790 | 5/20 | 0.89 |
| ▸ | CA12 | O43570 | 2/20 | 0.89 |
| ▸ | CA7 | P43166 | 3/20 | 0.76 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.76 |
| ▸ | MEN1 | O00255 | 5/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.74 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | GFER | P55789 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15888499 | 0.87 | CA1 (0.86) | CA1CA2CA9CA12CA7 | |
| SCHEMBL30628487 | 0.87 | CA1 (0.86) | CA1CA2CA9CA12CA7 | |
| SCHEMBL13401865 | 0.87 | CA1 (0.86) | CA1CA2CA9CA12CA7 | |
| SCHEMBL8868584 | 0.87 | CA2 (0.86) | CA1CA2CA9CA12CA7 | |
| SCHEMBL6046379 | 0.87 | MEN1 (0.90) | CA1CA2CA9CA12CA7 | |
| SCHEMBL31420450 | 0.86 | NPC1 (0.84) | CA1CA2CA9CA12NPC1 | |
| SCHEMBL11807861 | 0.86 | MEN1 (0.87) | CA1CA2CA9CA12CA7 | |
| SCHEMBL28582955 | 0.85 | MEN1 (1.00) | CA1CA2CA9CA12CA7 | |
| SCHEMBL11887789 | 0.85 | CA1 (0.82) | CA1CA2CA9CA12CA7 | |
| SCHEMBL4301505 | 0.84 | CA1 (0.80) | CA1CA2CA9CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140743-A2 | BLOOD IMAGING | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2009-11-26 | — | — | WO | disclosed |