Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 8/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | PRKACA | P17612 | 1/20 | 0.49 |
| ▸ | PRKACG | P22612 | 1/20 | 0.49 |
| ▸ | PRKACB | P22694 | 1/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 2/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 2/20 | 0.43 |
| ▸ | F9 | P00740 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13625773 | 0.93 | FAAH (0.51) | EGLN1MAOBMAOAFAAHROCK2 | |
| SCHEMBL4309249 | 0.82 | EGLN1 (0.51) | EGLN1MAOBMAOAFAAHROCK2 | |
| SCHEMBL4309518 | 0.79 | EGLN1 (0.51) | EGLN1MAOBMAOAROCK2PRKACA | |
| SCHEMBL4319371 | 0.79 | EGLN1 (0.46) | EGLN1FAAHROCK2PRKACAPRKACG | |
| SCHEMBL4310690 | 0.79 | CNR2 (0.46) | EGLN1ROCK2PRKACAPRKACGPRKACB | |
| SCHEMBL4310730 | 0.76 | EGLN1 (0.65) | EGLN1FAAHROCK2PRKACAPRKACG | |
| SCHEMBL4303188 | 0.75 | EGLN1 (0.52) | EGLN1ROCK2PRKACAPRKACGPRKACB | |
| SCHEMBL4313430 | 0.74 | EGLN1 (0.67) | EGLN1ROCK2PRKACAPRKACGPRKACB | |
| SCHEMBL4311056 | 0.74 | EGLN1 (0.48) | EGLN1MAOBMAOAFAAHROCK2 | |
| SCHEMBL4309178 | 0.71 | EGLN1 (0.51) | EGLN1MAOBFAAHROCK2PRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009134754-A1 | BENZOIMIDAZOLE GLYCINAMIDES AS PROLYL HYDROXYLASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2009-11-05 | — | — | WO | disclosed |