SCHEMBL4306515

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4304481	0.92	POLB (0.35)	SMN1; SMN2HTTLMNATSHRGAA
	SCHEMBL4311700	0.87	POLB (0.43)	CYP1A2TDP1HPGDSMN1; SMN2HTT
	SCHEMBL4309847	0.87	CYP1A2 (0.44)	CYP1A2CYP2D6TDP1HPGDSMN1; SMN2
	SCHEMBL4304641	0.84	CYP1A2 (0.45)	CYP1A2LMNATSHR
	SCHEMBL4314433	0.82	POLB (0.35)	CYP1A2SMN1; SMN2LMNAMEN1KMT2A
	SCHEMBL4311461	0.78	POLB (0.37)	CYP1A2CYP2D6TDP1SMN1; SMN2HTT
	SCHEMBL13667440	0.78	POLB (0.37)	CYP1A2CYP2D6TDP1SMN1; SMN2HTT
	SCHEMBL13667434	0.78	POLB (0.37)	CYP1A2CYP2D6TDP1SMN1; SMN2HTT
	SCHEMBL4314093	0.77	CCR3 (0.37)	CYP1A2CYP2D6TSHRMEN1KMT2A
	SCHEMBL4313007	0.76	POLB (0.37)	LMNARAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.