Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 10/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4307011 | 1.00 | RAB9A (0.74) | RAB9AKMT2ANPC1ATMTSHR | |
| SCHEMBL4151467 | 0.91 | RAB9A (0.70) | RAB9AKMT2ANPC1ATMTSHR | |
| SCHEMBL4005538 | 0.91 | RAB9A (0.70) | RAB9AKMT2ANPC1ATMTSHR | |
| SCHEMBL4005534 | 0.91 | RAB9A (0.70) | RAB9AKMT2ANPC1ATMTSHR | |
| SCHEMBL4006595 | 0.88 | KMT2A (0.68) | RAB9AKMT2ATSHRMEN1HSD11B1 | |
| SCHEMBL4006602 | 0.88 | KMT2A (0.68) | RAB9AKMT2ATSHRMEN1HSD11B1 | |
| SCHEMBL5950721 | 0.86 | RAB9A (0.63) | RAB9AKMT2ANPC1ATMTSHR | |
| SCHEMBL4009266 | 0.86 | RAB9A (0.63) | RAB9AKMT2ANPC1ATMTSHR | |
| SCHEMBL4009269 | 0.86 | RAB9A (0.63) | RAB9AKMT2ANPC1ATMTSHR | |
| SCHEMBL613408 | 0.85 | RAB9A (0.77) | RAB9AKMT2ANPC1ATMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778229-A4 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2009-06-17 | — | — | EP | disclosed |
| EP-1778229-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006020598-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-23 | — | — | WO | disclosed |