Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.42 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.42 |
| ▸ | SSU72 | Q9NP77 | 1/20 | 0.42 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1990967 | 0.93 | ACP1 (0.42) | ACP1PTPN12PTPN13SSU72GLRA1 | |
| SCHEMBL1989523 | 0.92 | PTGER1 (0.46) | ACP1PTPN12PTPN13SSU72GLRA1 | |
| SCHEMBL1989522 | 0.92 | PTGER1 (0.46) | ACP1PTPN12PTPN13SSU72GLRA1 | |
| SCHEMBL1995519 | 0.85 | KMT2A (0.45) | ACP1PTPN12PTPN13SSU72PTGER1 | |
| SCHEMBL1990350 | 0.84 | PTGER1 (0.51) | PTGER1PTGER4PTGER3PTGER2MRGPRX4 | |
| SCHEMBL1990348 | 0.84 | PTGER1 (0.51) | PTGER1PTGER4PTGER3PTGER2MRGPRX4 | |
| SCHEMBL1992690 | 0.82 | FOLH1 (0.42) | ACP1PTPN12PTPN13SSU72GLRA1 | |
| SCHEMBL1992692 | 0.82 | FOLH1 (0.42) | ACP1PTPN12PTPN13SSU72GLRA1 | |
| SCHEMBL2167258 | 0.82 | LRRK2 (0.46) | PTGER1LMNAALDH1A1HPGDRAB9A | |
| SCHEMBL15148415 | 0.82 | LRRK2 (0.46) | PTGER1LMNAALDH1A1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009126844-A2 | DERIVATIVES OF 3-(2-HYDROXY-5-METHYPHENYL)-N,N-DIISOPROPYL-3-PHENYLPROPYLAMINE AND METHODS OF USE THEREOF | CONCERT PHARMACEUTICALS INC. (US) | 2009-10-15 | — | — | WO | disclosed |