SCHEMBL4307336

SCHEMBL4307336

C=CC(=O)OCCSSCCOC(=O)C=C

nearest known ligand 0.60

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.60
ALDH1A1 P00352 4/20 0.60
TP53 P04637 3/20 0.60
HIF1A Q16665 3/20 0.60
CYP3A4 P08684 2/20 0.60
HSD17B10 Q99714 1/20 0.60
HPGD P15428 1/20 0.54
THRB P10828 2/20 0.44
MAPK1 P28482 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
ATM Q13315 1/20 0.32
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15591258 0.92 TSHR (0.52) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL12480064 0.92 TSHR (0.63) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL15591261 0.90 TSHR (0.50) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL28107880 0.90 TSHR (0.55) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL21318099 0.90 TSHR (0.60) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL21318071 0.90 TSHR (0.50) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL15583435 0.87 TSHR (0.47) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL10099800 0.86 TSHR (0.68) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL672392 0.86 TSHR (0.60) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL17035615 0.86 TSHR (0.50) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4688891-A2 COMPOSITIONS AND METHODS FOR MAKING A REVERSIBILY-CROSSLINKED POLYMER Braskem America, Inc. (US) 2026-02-11 EP claimed
WO-2025235568-A1 ETHYLENE BASED CO/TERPOLYMERS CONTAINING A HIGH PURITY -S-S- BASED DYNAMIC CROSSLINKER TO PRODUCE AN IN-REACTOR DYNAMIC MATERIAL BRASKEM AMERICA, INC. (US) 2025-11-13 WO claimed
WO-2025085640-A1 DYNAMICALLY CROSSLINKED ETHYLENE BASED POLYMERS FOR RE-PROCESSIBLE POLYOLEFINS VIA REACTIVE EXTRUSION BRASKEM AMERICA, INC. (US) 2025-04-24 WO claimed
US-20250129194-A1 DYNAMICALLY CROSSLINKED ETHYLENE BASED POLYMERS FOR RE-PROCESSIBLE POLYOLEFINS VIA REACTIVE EXTRUSION BRASKEM AMERICA INC (US) 2025-04-24 US claimed
EP-4453566-A2 CRITICALLY-LOCKED MECHANICAL METAMATERIAL FOR HYPER-RESPONSIVE MOLECULAR PROFILING National University of Singapore (SG) 2024-10-30 EP claimed
WO-2024218251-A1 POLYMER DISPERSIONS OF POLYMERS P BASF SE (DE) 2024-10-24 WO claimed
WO-2024206783-A2 COMPOSITIONS AND METHODS FOR MAKING A REVERSIBILY-CROSSLINKED POLYMER BRASKEM AMERICA, INC. (US) 2024-10-03 WO claimed
US-20240327554-A1 COMPOSITIONS AND METHODS FOR MAKING A REVERSIBILY-CROSSLINKED POLYMER BRASKEM AMERICA, INC. 2024-10-03 US claimed
CN-117467160-A Photo-crosslinked self-healing gelatin hydrogel and preparation method thereof 淮北师范大学 2024-01-30 CN claimed
WO-2023121567-A2 CRITICALLY-LOCKED MECHANICAL METAMATERIAL FOR HYPER-RESPONSIVE MOLECULAR PROFILING NATIONAL UNIVERSITY OF SINGAPORE (SG) 2023-06-29 WO claimed
CN-122011975-A Force-sensitive self-reinforced adhesive for silicon-based negative electrode of lithium ion battery, and preparation method and application thereof 湖南智电谷能源科技有限公司 2026-05-12 CN disclosed
EP-4688891-A2 COMPOSITIONS AND METHODS FOR MAKING A REVERSIBILY-CROSSLINKED POLYMER Braskem America, Inc. (US) 2026-02-11 EP disclosed
CN-121449829-A Super-tough temperature-resistant self-repairing copolymer based on SBS acrylic ester dynamic synergistic reinforcement and preparation method thereof 安徽富印新材料股份有限公司 2026-02-03 CN disclosed
WO-2025235568-A1 ETHYLENE BASED CO/TERPOLYMERS CONTAINING A HIGH PURITY -S-S- BASED DYNAMIC CROSSLINKER TO PRODUCE AN IN-REACTOR DYNAMIC MATERIAL BRASKEM AMERICA, INC. (US) 2025-11-13 WO disclosed
US-20250067732-A1 CRITICALLY-LOCKED MECHANICAL METAMATERIAL FOR HYPER-RESPONSIVE MOLECULAR PROFILING NATIONAL UNIVERSITY OF SINGAPORE (SG) 2025-02-27 US disclosed
WO-2013056113-A1 NANOCOMPOSITES OF GOLD AND POLYMERS THE JOHNS HOPKINS UNIVERSITY (US) 2013-04-18 WO disclosed
US-20120301512-A1 Tetrary Gene Delivery System for Gene Therapy and Methods of Its Use UNIVERSITY OF SOUTH CAROLINA (US) 2012-11-29 US disclosed
US-20120114759-A1 PEPTIDE/PARTICLE DELIVERY SYSTEMS THE JOHNS HOPKINS UNIVERSITY (US) 2012-05-10 US disclosed
US-20120114759-A1 PEPTIDE/PARTICLE DELIVERY SYSTEMS THE JOHNS HOPKINS UNIVERSITY (US) 2012-05-10 US disclosed
WO-2009132206-A1 COMPOSITIONS AND METHODS FOR INTRACELLULAR DELIVERY AND RELEASE OF CARGO LIQUIDIA TECHNOLOGIES, INC. (US) 2009-10-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120114759-A1 PEPTIDE/PARTICLE DELIVERY SYSTEMS VEGFA, IAPP, FLT1 TSHR 2490/4885ALDH1A1 4007/4885TP53 324/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.