SCHEMBL672392

SCHEMBL672392

C=CC(=O)OCCSCCOC(=O)C=C

nearest known ligand 0.60

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.60
ALDH1A1 P00352 4/20 0.60
TP53 P04637 3/20 0.60
HIF1A Q16665 3/20 0.60
CYP3A4 P08684 2/20 0.60
HSD17B10 Q99714 1/20 0.60
HPGD P15428 1/20 0.54
THRB P10828 2/20 0.44
MAPK1 P28482 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
ATM Q13315 1/20 0.32
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL672840 0.98 TSHR (0.58) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL7563889 0.98 TSHR (0.58) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL673220 0.98 TSHR (0.58) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL10427197 0.94 TSHR (0.65) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL10427255 0.94 TSHR (0.59) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL10426942 0.94 TSHR (0.59) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL11647433 0.92 TSHR (0.63) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL29940620 0.92 TSHR (0.63) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL10150608 0.90 TSHR (0.60) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL29763105 0.90 TSHR (0.50) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12195618-B2 3D printable resin compositions AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2025-01-14 US claimed
CN-118994654-A Additive and polypropylene material and preparation method thereof 国家能源集团宁夏煤业有限责任公司 2024-11-22 CN claimed
US-12015122-B2 Silicon-based energy storage devices with carboxylic ether, carboxylic acid based salt, or acrylate electrolyte containing electrolyte additives ENEVATE CORPORATION (US) 2024-06-18 US claimed
US-20230122021-A1 3D Printable Resin Compositions AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2023-04-20 US claimed
CN-111712523-B Ophthalmic product composition 爱尔兰眼力健公司 2023-01-03 CN claimed
EP-3728339-B1 COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS AMO Ireland (IE) 2022-07-06 EP claimed
US-11359031-B2 Composition for ophthalmological products Johnson & Johnson Surgical Vision, Inc. (US) 2022-06-14 US claimed
US-6194511-B1 COMPRISING POLYMERIZABLE MONOMER CONTAINING SULFUR-CONTAINING (METH)ACRYLATE POLYMERIZABLE MONOMER AND PHOTOCHROMIC COMPOUND TOKUYAMA CORPORATION (JP) 2001-02-27 US claimed
US-20260140398-A1 OPTICAL MATERIAL COMPOSITION, CURED BODY, OPTICAL ARTICLE, LENS, AND SPECTACLES TOKUYAMA CORPORATION (JP) 2026-05-21 US disclosed
EP-3901185-B1 CURABLE COMPOSITION FOR OPTICAL MATERIALS, AND OPTICAL MATERIAL TOKUYAMA CORP (JP) 2026-03-25 EP disclosed
WO-2026044148-A1 LOW GLOSS ELECTRON BEAM CURABLE COATING COMPOSITIONS PPG INDUSTRIES OHIO, INC. (US) 2026-02-26 WO disclosed
EP-4696722-A1 (METH)ACRYLATE, CURABLE COMPOSITION, CURED BODY, LAMINATE, OPTICAL ARTICLE, LENS, AND EYEGLASSES TOKUYAMA CORPORATION (JP) 2026-02-18 EP disclosed
US-12552745-B2 Compound for optical materials, curable composition, cured body, and optical article TOKUYAMA CORPORATION (JP) 2026-02-17 US disclosed
EP-4644435-A1 URETHANE (METH)ACRYLATE, CURABLE COMPOSITION, CURED BODY, LAMINATE, OPTICAL ARTICLE, LENSES, AND EYEGLASSES TOKUYAMA CORPORATION (JP) 2025-11-05 EP disclosed
EP-1427763-A1 METHOD FOR THE PRODUCTION OF POLYMERS AND COPOLYMERS FROM ACRYLIC COMPOUNDS Röhm GmbH & Co. KG (DE) 2004-06-16 EP disclosed
WO-2003022897-A1 METHOD FOR THE PRODUCTION OF POLYMERS AND COPOLYMERS FROM ACRYLIC COMPOUNDS Röhm GmbH & Co. KG (DE) 2003-03-20 WO disclosed
EP-0940694-B1 Photochromic curable composition TOKUYAMA CORP (JP) 2002-08-14 EP disclosed
EP-1130038-A1 CURABLE COMPOSITION TOKUYAMA CORPORATION (JP) 2001-09-05 EP disclosed
US-6194511-B1 COMPRISING POLYMERIZABLE MONOMER CONTAINING SULFUR-CONTAINING (METH)ACRYLATE POLYMERIZABLE MONOMER AND PHOTOCHROMIC COMPOUND TOKUYAMA CORPORATION (JP) 2001-02-27 US disclosed
EP-0940694-A1 Photochromic curable composition TOKUYAMA CORPORATION (JP) 1999-09-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552745-B2 Compound for optical materials, curable composition, cured body, and optical article C5, SCO2, ZYX TSHR 3533/4885ALDH1A1 1308/4885TP53 4357/4885
US-20260140398-A1 OPTICAL MATERIAL COMPOSITION, CURED BODY, OPTICAL ARTICLE, LENS, AND SPECTACLES CRYAA, FEM1B, MAPRE1 TSHR 4218/4885ALDH1A1 588/4885TP53 4504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.