Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | XBP1 | P17861 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL428660 | 0.89 | NPC1 (0.34) | NPC1ALDH1A1MAPTXBP1RAB9A | |
| SCHEMBL428552 | 0.85 | SPR (0.30) | — | |
| SCHEMBL464644 | 0.84 | MAPT (0.48) | NPC1ALDH1A1MAPTXBP1RAB9A | |
| SCHEMBL430381 | 0.84 | MAPT (0.48) | NPC1ALDH1A1MAPTXBP1RAB9A | |
| SCHEMBL430763 | 0.83 | PROKR1 (0.31) | NPC1ALDH1A1MAPTXBP1RAB9A | |
| SCHEMBL428616 | 0.82 | MAPT (0.46) | NPC1ALDH1A1MAPTXBP1RAB9A | |
| SCHEMBL427516 | 0.81 | PSEN1 (0.35) | — | |
| SCHEMBL428636 | 0.79 | — | — | |
| SCHEMBL428566 | 0.78 | KDM4E (0.32) | MAPTSMN1; SMN2NPSR1KDM4E | |
| SCHEMBL427490 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2375898-B1 | NOVEL HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-09-16 | — | — | EP | disclosed |
| US-8889595-B2 | Herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2014-11-18 | — | — | US | disclosed |
| US-8889595-B2 | Herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2014-11-18 | — | — | US | disclosed |
| US-20120065064-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065064-A1 | NOVEL HERBICIDES | DDT, CYP1B1, CYP4X1 | NPC1 4593/4885ALDH1A1 10/4885MAPT 3792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.