Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 11/20 | 0.75 |
| ▸ | TLR7 | Q9NYK1 | 19/20 | 0.62 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4314855 | 0.91 | TLR8 (0.67) | TLR8TLR7NUDT1 | |
| SCHEMBL1894343 | 0.91 | TLR8 (0.80) | TLR8TLR7NUDT1 | |
| SCHEMBL4315878 | 0.91 | TLR8 (0.70) | TLR8TLR7NUDT1 | |
| SCHEMBL4311373 | 0.90 | TLR8 (0.66) | TLR8TLR7NUDT1 | |
| SCHEMBL17951269 | 0.88 | TLR8 (0.88) | TLR8TLR7NUDT1 | |
| SCHEMBL13999937 | 0.87 | TLR8 (0.86) | TLR8TLR7NUDT1 | |
| SCHEMBL22331129 | 0.87 | TLR8 (0.78) | TLR8TLR7NUDT1 | |
| SCHEMBL6103528 | 0.87 | TLR8 (0.78) | TLR8TLR7NUDT1 | |
| SCHEMBL5111244 | 0.86 | TLR8 (1.00) | TLR8TLR7NUDT1 | |
| Hydrochloric Acid SCHEMBL6105387 | 0.86 | TLR8 (0.77) | TLR8TLR7NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8735421-B2 | Imidazoquinolinyl sulfonamides | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-05-27 | — | — | US | disclosed |
| US-20090062272-A1 | IMIDAZOQUINOLINYL SULFONAMIDES | 3M INNOVATIVE PROPERTIES COMPANY | 2009-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062272-A1 | IMIDAZOQUINOLINYL SULFONAMIDES | IL2, EIF2AK2, IFNG | TLR8 106/4885TLR7 167/4885NUDT1 1301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.