Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 4/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4312944 | 0.98 | NAAA (0.38) | NAAAEPHX1HTTCYP2C19LMNA | |
| SCHEMBL4307836 | 0.97 | NAAA (0.40) | NAAAEPHX1HTTCYP2C19LMNA | |
| SCHEMBL2901152 | 0.95 | NAAA (0.40) | NAAAEPHX1HTTCYP2C19CYP19A1 | |
| SCHEMBL4314580 | 0.93 | NAAA (0.39) | NAAAEPHX1HTTCYP2C19CYP19A1 | |
| SCHEMBL8579936 | 0.87 | EPHX1 (0.42) | NAAAEPHX1HTTCYP2C19CYP19A1 | |
| SCHEMBL1559459 | 0.87 | EPHX1 (0.42) | NAAAEPHX1HTTCYP2C19CYP19A1 | |
| SCHEMBL9034880 | 0.85 | NAAA (0.30) | NAAA | |
| SCHEMBL5245472 | 0.85 | EPHX1 (0.39) | NAAAEPHX1HTTCYP2C19CYP19A1 | |
| SCHEMBL11590755 | 0.83 | NAAA (0.58) | NAAAEPHX1HTTL3MBTL1 | |
| SCHEMBL11590153 | 0.83 | NAAA (0.58) | NAAAEPHX1HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136965-A1 | COMPOSITIONS AND METHODS COMPRISING CAPURAMYCIN ANALOGUES | SEQUELLA, INC. (US) | 2009-11-12 | — | — | WO | disclosed |