⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1132940 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL27857854 | 0.97 | — | — | |
| SCHEMBL3970325 | 0.92 | — | — | |
| SCHEMBL20334775 | 0.92 | — | — | |
| SCHEMBL3469054 | 0.90 | HIF1A (0.46) | — | |
| SCHEMBL2500151 | 0.79 | — | — | |
| SCHEMBL447351 | 0.79 | — | — | |
| SCHEMBL21022704 | 0.79 | — | — | |
| SCHEMBL21090095 | 0.79 | HIF1A (0.38) | — | |
| SCHEMBL18735919 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0938286-B1 | REDUCTION OF HAIR GROWTH | GILLETTE CO (US) | 2003-11-05 | — | — | EP | claimed |
| EP-4112631-A1 | CASPASE-2 INHIBITOR COMPOUNDS | Kintsugi Therapeutics S.L. (ES) | 2023-01-04 | — | — | EP | disclosed |
| EP-3885337-A1 | FTO INHIBITORS | National Institute Of Biological Sciences, Beijing (CN) | 2021-09-29 | — | — | EP | disclosed |
| WO-2020228478-A1 | ANTI-TUMOR DIAZOBICYCLIC APOPTOSIS PROTEIN INHIBITOR | 南京华威医药科技集团有限公司 | 2020-11-19 | — | — | WO | disclosed |
| US-10441571-B2 | Spiro-lactam NMDA receptor modulators and uses thereof | APTINYX INC. (US) | 2019-10-15 | — | — | US | disclosed |
| EP-3305900-A1 | ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES | Nuevolution A/S (DK) | 2018-04-11 | — | — | EP | disclosed |
| WO-2012166665-A2 | BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS, INC. (US) | 2012-12-06 | — | — | WO | disclosed |
| EP-2084519-A2 | ADVANCED DRUG DEVELOPMENT AND MANUFACTURING | Los Alamos National Security, LLC (US) | 2009-08-05 | — | — | EP | disclosed |
| WO-2008127291-A2 | ADVANCED DRUG DEVELOPMENT AND MANUFACTURING | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2008-10-23 | — | — | WO | disclosed |
| WO-2008002039-A1 | QUINAZOLINE DERIVATIVES FOR INHIBITING THE GROWTH OF CANCER CELL | HANMI PHARM. CO., LTD. (KR) | 2008-01-03 | — | — | WO | disclosed |
| EP-1181274-A4 | IMINOCYCLITOL INHIBITORS OF HEXOAMINIDASE AND GLYCOSIDASE | SCRIPPS RESEARCH INST (US) | 2005-08-17 | — | — | EP | disclosed |
| EP-0938286-B1 | REDUCTION OF HAIR GROWTH | GILLETTE CO (US) | 2003-11-05 | — | — | EP | disclosed |
| EP-1181274-A1 | IMINOCYCLITOL INHIBITORS OF HEXOAMINIDASE AND GLYCOSIDASE | The Scripps Research Institute (US) | 2002-02-27 | — | — | EP | disclosed |
| WO-2000068194-A1 | IMINOCYCLITOL INHIBITORS OF HEXOAMINIDASE AND GLYCOSIDASE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2000-11-16 | — | — | WO | disclosed |
| EP-0938286-A1 | REDUCTION OF HAIR GROWTH | HANDELMAN, Joseph H. (US) | 1999-09-01 | — | — | EP | disclosed |
| US-5908867-A | Reduction of hair growth | HENRY JAMES P (US) | 1999-06-01 | — | — | US | disclosed |
| WO-1998003149-A1 | REDUCTION OF HAIR GROWTH | HANDELMAN, JOSEPH, H. (US) | 1998-01-29 | — | — | WO | disclosed |