Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.73 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.73 |
| ▸ | THRA | P10827 | 9/20 | 0.61 |
| ▸ | THRB | P10828 | 9/20 | 0.61 |
| ▸ | RARB | P10826 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | RARA | P10276 | 1/20 | 0.61 |
| ▸ | MTOR | P42345 | 1/20 | 0.61 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6069166 | 1.00 | CYP4A11 (0.73) | CYP4A11CYP4F2THRATHRBRARB | |
| SCHEMBL6024028 | 1.00 | CYP4A11 (0.73) | CYP4A11CYP4F2THRATHRBRARB | |
| SCHEMBL15174466 | 1.00 | CYP4A11 (0.73) | CYP4A11CYP4F2THRATHRBRARB | |
| SCHEMBL10986414 | 1.00 | CYP4A11 (0.73) | CYP4A11CYP4F2THRATHRBRARB | |
| SCHEMBL12814607 | 1.00 | CYP4A11 (0.73) | CYP4A11CYP4F2THRATHRBRARB | |
| SCHEMBL11028588 | 1.00 | CYP4A11 (0.73) | CYP4A11CYP4F2THRATHRBRARB | |
| SCHEMBL14660877 | 1.00 | CYP4A11 (0.73) | CYP4A11CYP4F2THRATHRBRARB | |
| SCHEMBL8044139 | 0.98 | CYP4A11 (0.75) | CYP4A11CYP4F2THRATHRBRARB | |
| SCHEMBL2401275 | 0.95 | RARB (0.69) | CYP4A11CYP4F2THRATHRBRARB | |
| SCHEMBL20874436 | 0.95 | RARB (0.69) | CYP4A11CYP4F2THRATHRBRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4180475-A | POSITIVE ANISOTROPY OF DIELECTRIC CONSTANTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-12-25 | — | — | US | claimed |
| US-20230072658-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-03-09 | — | — | US | disclosed |
| CN-110520413-B | Macrocyclic broad spectrum antibiotics | 阿奇克斯制药公司 | 2023-02-17 | — | — | CN | disclosed |
| CN-108884058-B | Macrocyclic broad spectrum antibiotics | 阿奇克斯制药公司 | 2022-04-29 | — | — | CN | disclosed |
| EP-3248061-B1 | LIGHT MODULATION ELEMENT | MERCK PATENT GMBH (DE) | 2020-10-14 | — | — | EP | disclosed |
| WO-2016022881-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AND METHODS OF USE AND MANUFACTURE | DUQUESNE UNIVERSITY OF THE HOLY SPIRIT (US) | 2016-02-11 | — | — | WO | disclosed |
| US-9029565-B1 | Fused ring indeno compounds for preparation of photochromic compounds | TRANSITIONS OPTICAL, INC. (US) | 2015-05-12 | — | — | US | disclosed |
| US-9000209-B2 | Method of regioselective synthesis of substituted benzoates | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2015-04-07 | — | — | US | disclosed |
| US-20140288324-A1 | METHOD OF REGIOSELECTIVE SYNTHESIS OF SUBSTITUTED BENZOATES | NATIONAL SCIENCE FOUNDATION | 2014-09-25 | — | — | US | disclosed |
| WO-2013185740-A1 | A METHOD FOR THE PREPARATION OF FINGOLIMOD | ZENTIVA, K.S. (CZ) | 2013-12-19 | — | — | WO | disclosed |
| WO-2013015918-A1 | METHOD OF REGIOSELECTIVE SYNTHESIS OF SUBSTITUTED BENZOATES | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2013-01-31 | — | — | WO | disclosed |
| WO-2009133045-A1 | NEW BORANE-AMINE COMPLEXES AND THEIR APPLICATION IN SUZUKI-TYPE CROSS -COUPLING REACTIONS | BASF SE (DE) | 2009-11-05 | — | — | WO | disclosed |
| WO-2009133045-A1 | NEW BORANE-AMINE COMPLEXES AND THEIR APPLICATION IN SUZUKI-TYPE CROSS -COUPLING REACTIONS | BASF SE (DE) | 2009-11-05 | — | — | WO | disclosed |
| US-6616989-B1 | A switching and/or display device | CLARIANT INTERNATIONAL LTD. (CH) | 2003-09-09 | — | — | US | disclosed |
| US-4507450-A | COORDINATION CATALYSTS | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1985-03-26 | — | — | US | disclosed |
| US-4229558-A | HAVING HIGH ISOTACTIC INDEX BY USING A CATALYST PREPARED FROM A MAGNESIUM GRIGNARD REAGENT, TITANIUM HALIDE AN ETHER AND A CARBOXYLIC ESTER COMBINED WITH AN ORGANOALUMINUM COMPOUND | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1980-10-21 | — | — | US | disclosed |
| US-4198130-A | Liquid crystal mixtures | HOFFMANN-LA ROCHE INC. (US) | 1980-04-15 | — | — | US | disclosed |
| US-4180475-A | POSITIVE ANISOTROPY OF DIELECTRIC CONSTANTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140288324-A1 | METHOD OF REGIOSELECTIVE SYNTHESIS OF SUBSTITUTED BENZOATES | MAL2, PAH, ME3 | CYP4A11 13/4885CYP4F2 237/4885THRA 4422/4885 |
| US-20230072658-A1 | SMARCA DEGRADERS AND USES THEREOF | SMARCA1, SMARCB1, SMARCE1 | CYP4A11 3925/4885CYP4F2 4684/4885THRA 3676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.