Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 6/20 | 0.43 |
| ▸ | CA1 | P00915 | 9/20 | 0.42 |
| ▸ | CA2 | P00918 | 9/20 | 0.42 |
| ▸ | CA9 | Q16790 | 6/20 | 0.42 |
| ▸ | CA12 | O43570 | 4/20 | 0.42 |
| ▸ | CA6 | P23280 | 3/20 | 0.42 |
| ▸ | CA5A | P35218 | 3/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31315370 | 0.85 | PTGES2 (0.55) | PTGES2CA1CA2CA9CA12 | |
| SCHEMBL29469865 | 0.85 | PTGES2 (0.55) | PTGES2CA1CA2CA9CA12 | |
| SCHEMBL2247901 | 0.85 | PTGES2 (0.55) | PTGES2CA1CA2CA9CA12 | |
| SCHEMBL1622136 | 0.85 | PTGES2 (0.55) | PTGES2CA1CA2CA9CA12 | |
| SCHEMBL8415242 | 0.82 | PTGES2 (0.43) | PTGES2CA1CA2CA9CA12 | |
| SCHEMBL11169369 | 0.82 | PTGES2 (0.46) | PTGES2CA1CA2CA9CA12 | |
| SCHEMBL29469971 | 0.81 | CA2 (0.44) | PTGES2CA1CA2CA9CA12 | |
| SCHEMBL1111521 | 0.81 | CA2 (0.44) | PTGES2CA1CA2CA9CA12 | |
| SCHEMBL27517701 | 0.79 | PTGES2 (0.44) | PTGES2CA1CA2CA9CA12 | |
| SCHEMBL11014063 | 0.77 | PTGES2 (0.42) | PTGES2CA1CA2CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140743-A2 | BLOOD IMAGING | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2009-11-26 | — | — | WO | disclosed |