Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR9 | P51686 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 8/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4323857 | 0.96 | MAPT (0.39) | CCR9MAPTTHRBTP53MC4R | |
| SCHEMBL4307331 | 0.96 | CCR9 (0.39) | CCR9MAPTTHRBTP53MC4R | |
| SCHEMBL4310962 | 0.95 | MAPT (0.40) | CCR9MAPTTHRBTP53MC4R | |
| SCHEMBL4311922 | 0.94 | MAPT (0.38) | CCR9MAPTTHRBMC4R | |
| SCHEMBL4311871 | 0.93 | CCR9 (0.38) | CCR9MAPTTHRBTP53MC4R | |
| SCHEMBL4305287 | 0.93 | CCR9 (0.38) | CCR9MAPTTHRBMC4RMMP2 | |
| SCHEMBL4314718 | 0.92 | CCR9 (0.42) | CCR9MAPTTHRBTP53MTNR1A | |
| SCHEMBL4311531 | 0.91 | CCR9 (0.35) | CCR9MAPTTHRBTP53MC4R | |
| SCHEMBL4312933 | 0.89 | MAPT (0.40) | CCR9MAPTTHRBMTNR1AMTNR1B | |
| SCHEMBL4320903 | 0.88 | OXER1 (0.39) | CCR9MAPTTHRBMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090062280-A1 | Ophthalmic Compositions for Treating Ocular Hypertension | MERCK SHARP & DOHME CORP. | 2009-03-05 | — | — | US | claimed |
| US-20090062280-A1 | Ophthalmic Compositions for Treating Ocular Hypertension | MERCK SHARP & DOHME CORP. | 2009-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062280-A1 | Ophthalmic Compositions for Treating Ocular Hypertension | KCNN3, KCNN1, KCNN2 | CCR9 4698/4885MAPT 498/4885THRB 2231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.