SCHEMBL4308995

SCHEMBL4308995

COC(=O)c1cc(Cl)ccc1[O]

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 1/20 0.61
SLC6A3 Q01959 2/20 0.53
SLC6A4 P31645 1/20 0.53
NR4A2 P43354 2/20 0.53
RXFP1 Q9HBX9 1/20 0.48
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
ALDH1A1 P00352 4/20 0.46
LMNA P02545 3/20 0.46
KDM4E B2RXH2 3/20 0.46
MAPT P10636 2/20 0.44
HTT P42858 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
ALPL P05186 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
NPC1 O15118 1/20 0.44
NFKB1 P19838 1/20 0.44
RAB9A P51151 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6100118 0.84 ABL1 (0.70) ABL1SLC6A3SLC6A4NR4A2RXFP1
SCHEMBL4363906 0.82 ABL1 (0.62) ABL1SLC6A3SLC6A4NR4A2RXFP1
SCHEMBL26661413 0.81 ABL1 (0.61) ABL1SLC6A3SLC6A4NR4A2RXFP1
SCHEMBL2452734 0.81 ABL1 (0.61) ABL1SLC6A3SLC6A4NR4A2RXFP1
SCHEMBL11300844 0.81 ABL1 (0.61) ABL1SLC6A3SLC6A4NR4A2RXFP1
SCHEMBL29752578 0.81 ABL1 (0.61) ABL1SLC6A3SLC6A4NR4A2RXFP1
SCHEMBL29406512 0.81 ABL1 (0.61) ABL1SLC6A3SLC6A4NR4A2RXFP1
SCHEMBL123068 0.81 CA1 (0.67) ABL1SLC6A3SLC6A4NR4A2MEN1
SCHEMBL1462096 0.81 ABL1 (0.61) ABL1SLC6A3SLC6A4NR4A2RXFP1
SCHEMBL28734830 0.80 ABL1 (0.56) ABL1SLC6A3SLC6A4NR4A2RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE40697-E1 Method for making an aromatic polycarbonate SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-04-07 US disclosed
EP-1519831-A1 METHOD FOR MAKING AN AROMATIC POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2005-04-06 EP disclosed
US-6790929-B2 EXTRUSION GRAFTING AN OLIGOMERIZED POLYCARBONATE IN METHYL SALICYLATE SOLUTION, HEATING TO DESOLVENTIZE; A HIGH LEVEL OF ENDCAPPING, LOW LEVELS OF RESIDUAL SOLVENT GENERAL ELECTRIC COMPANY 2004-09-14 US disclosed
US-20030236384-A1 METHOD FOR MAKING AN AROMATIC POLYCARBONATE GENERAL ELECTRIC COMPANY 2003-12-25 US disclosed
WO-2003106149-A1 METHOD FOR MAKING AN AROMATIC POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2003-12-24 WO disclosed
US-20030232957-A1 Method for making an aromatic polycarbonate GENERAL ELECTRIC COMPANY 2003-12-18 US disclosed